TLS Online TPP Program

#Question id: 768


MicroRNAs are important gene regulators, but the miRNAs are also regulated in turn by other RNAs. Which, if any, of the following classes of RNA are not known to contain RNAs that regulate miRNAs?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Pseudogene RNA

  2. Ribosomal RNA

  3. Long noncoding RNA

  4. Circular RNA

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TLS Online TPP Program

#Question id: 865

#Unit 1. Molecules and their Interaction Relevant to Biology

In autophagy, the endoplasmic reticulum (ER) first gives rise to a cup-shaped, membranous cisterna called the______

TLS Online TPP Program

#Question id: 864

#Unit 1. Molecules and their Interaction Relevant to Biology

Which one is not the appropriate function of Heat Shock Proteins;

TLS Online TPP Program

#Question id: 862

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the following

lysosomal protein degradation pathwaysFound in
1. Nonselectivea-well-nourished cells

i-containing the pentapeptide

Lys-Phe-Glu-Arg-Gln

2- Selectiveb-starving cells

TLS Online TPP Program

#Question id: 861

#Unit 1. Molecules and their Interaction Relevant to Biology

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of

i. Only 2 to 3 minutes,

B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of

ii. >10 hours in prokaryotes

iii. >20 hours in eukaryotes.

TLS Online TPP Program

#Question id: 860

#Unit 1. Molecules and their Interaction Relevant to Biology

Select true ‘T’ AND false ‘F’ about ubiquitinylation

I. These ubiquitin-like modifiers control processes as diverse as nuclear import,

II. Regulated by the ubiquitin-like modifier Sumo, and autophagy,

III. Regulated by the ubiquitin-like modifier Atg8.

IV. For a protein to be efficiently degraded, it must be linked to a chain of at least four tandemly linked ubiquitin molecules in which Lys 34 of each ubiquitin forms an isopeptide bond with the C-terminal carboxyl group of the following ubiquitin.

TLS Online TPP Program

#Question id: 654

#Unit 1. Molecules and their Interaction Relevant to Biology

Which pair represents different conformations?