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TLS Online TPP Program

#Question id: 9150

For mountain ranges that are subjected to prevailing winds, why is the climate drier on the leeward (downwind) side?

#Unit 9. Diversity of Life Forms
  1. Deserts create dry conditions on the leeward side of mountain ranges.

  2. The sun illuminates the leeward side of mountain ranges at a more direct angle, converting to heat energy, which evaporates most of the water present.

  3. Pushed by the prevailing winds on the windward side, air is forced to rise, cool, condense, and drop its precipitation, leaving drier air to descend the leeward side.

  4. Air masses pushed by the prevailing winds are stopped by mountain ranges and the moisture is used up in the stagnant air masses on the leeward side.

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TLS Online TPP Program

#Question id: 909

#Unit 1. Molecules and their Interaction Relevant to Biology

Most proteins denature at both high and low pH. At high pH, the ionization of internal tyrosines is thought to be the main destabilizing influence, whereas at low pH, the protonation of buried histidines. A titration curve for the unfolding of the enzyme ribonuclease is shown in Figure. Given the relation between the titration curves for protein unfolding and histidine protonation, which of the following conclusion can be drawn correctly?

A. The sharp transition in graph indicates a highly cooperative process; when the protein starts to unfold, it completes the process rapidly

B. The sharp transition in graph indicates a highly noncooperative process

C. Several buried histidines can ionize when the chain starts to unfold, so that when one goes, they all go together due to cooperative behaviour of protein folding

D. Buried histidine (pK of 4 in this example) becomes accessible to solvent, its pK will shift toward its normal value of 6, significantly steepening its titration curve.
TLS Online TPP Program

#Question id: 908

#Unit 1. Molecules and their Interaction Relevant to Biology

Molecular chaperones are a class of proteins that play a role
TLS Online TPP Program

#Question id: 907

#Unit 1. Molecules and their Interaction Relevant to Biology

Thermodynamics of protein folding is depicted as a free energy vs folding process:

Choose the correct match for regions mentioned in the figure

A.

1. Molten globule

B.

2. Unfolded

C.

3. Transition state

D.

4. Folded

TLS Online TPP Program

#Question id: 906

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is least likely to result in protein denaturation?
TLS Online TPP Program

#Question id: 905

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct about chaperones

A) renature and denatured proteins.

B) help cells repair damage due to heat shock.

C) assist protein self assembly.

D) donot use ATP to fold proteins.
TLS Online TPP Program

#Question id: 904

#Unit 1. Molecules and their Interaction Relevant to Biology

In addition to self assembly, some proteins fold with the help of