#Question id: 10609
#Unit 10. Ecological Principles
The observation that members of a population are uniformly distributed suggests that
#Question id: 23552
#General Aptitude
#Question id: 17666
#Unit 11. Evolution and Behavior
#Question id: 4934
#Unit 11. Evolution and Behavior
What is another hypothesis regarding the formation of polymers such as proteins and nucleic acids?
#Question id: 1520
#Unit 4. Cell Communication and Cell Signaling
Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.
A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.
B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.
C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.
D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.
Which of the following statements are correct?