Programmed cell death, or apoptosis, is an essential part of animal development. In the nematode, with its invariant cell lineage, particular cell lineages or particular cells within specific lineages are destined to end in programmed cell death, and it was this feature that allowed the identification of the process and the analysis of its genetic control.

Which of the following combination of genes are correct?

#Question id: 8950

#Unit 9. Diversity of Life Forms

#Question id: 1523

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to the apoptosis which is induced by trophic factors.

A. The presence of specific trophic factors (e.g., NGF) leads to activation of their cognate receptor tyrosine kinases (e.g., TrkA) and activation of the PKB pathway.

B. DNA damage or ultraviolet irradiation leads to induction of synthesis of the BH3-only Puma protein. Puma binds to Bak and Bax as well as to Bcl-2, allowing Bak and Bax to form oligomeric pores.

C. Removal of a cell from its substratum disrupts integrin signaling, leading to release of the BH3-only Bim protein from the cytoskeleton.

D. Binding of extracellular death signals, such as tumor necrosis factor and Fas ligand, to their receptors oligomerizes an associated protein (FADD), which in turn triggers the caspase cascade, leading to cell murder by apoptosis.

Which of the following pathway does not belong to the trophic factor inducing apoptotic pathway?

#Question id: 10235

#Unit 10. Ecological Principles

Following some observation is correct about species of P, Q and R

A) Species P and R have generalized nich while Q has specialized nich

B) Species P and R have specialized nich while Q has generalized nich

C) Species P and R are more prone to extinct than Q species

D) Species Q is more prone to extinct than either P or R species

#Question id: 930

#Unit 1. Molecules and their Interaction Relevant to Biology

Ketone bodies are formed in the liver and transported to the extrahepatic tissues mainly as:

#Question id: 15529

#Unit 4. Cell Communication and Cell Signaling