#Question id: 9221
#Unit 9. Diversity of Life Forms
The primary difference between the small-population approach and the declining-population approach to biodiversity recovery is that ________.
#Question id: 7753
#Unit 5. Developmental Biology
#Question id: 23195
#Unit 13. Methods in Biology
#Question id: 3631
#Unit 8. Inheritance Biology
Six different mutations 1 to 6, from the following results of functional allelism tests whereby the mutants were crossed with each other, determine location of mutant gene.
#Question id: 15306
#Unit 4. Cell Communication and Cell Signaling
The transformation of a normal cell to a cancer cell is accompanied by the loss of function of one or more tumor‐suppressor genes. High‐throughput sequencing studies have identified hundreds of genes that are implicated as tumor suppressors in humans. Some of the better characterized genes;
Gene |
Primary tumor |
Proposed function |
i) APC |
Colorectal |
Binds β
‐catenin acting as transcription factor |
ii) BRCA1 |
Breast |
DNA repair |
iii) MSH2, MLH1 |
Melanoma, pancreatic |
p16: Cdk inhibitor ARF: stabilizes p53 |
iv) E‐Cadherin |
Breast, colon |
Cell adhesion molecule |
v) INK4a |
Colorectal |
Mismatch repair |
vi) NF1 |
Neurofibromas |
Activates GTPase of Ras |
Choose incorrect matching regarding tumor‐suppressor genes/primary tumor/proposed functions; |