TLS Online TPP Program

#Question id: 11486


The contraction of skeletal muscles is based on ________

#Unit 7. System Physiology – Animal
  1. myosin filaments coiling up to become shorter
  2. actin and myosin filaments both coiling up to become shorter
  3. actin cross-bridges binding to myosin and transitioning from a high-energy to a low-energy state
  4. myosin cross-bridges binding to actin and transitioning from a high-energy to a low-energy state
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TLS Online TPP Program

#Question id: 4944

#Unit 11. Evolution and Behavior

What is true of the amino acids that might have been delivered to Earth within carbonaceous chondrites?

TLS Online TPP Program

#Question id: 14686

#Unit 4. Cell Communication and Cell Signaling

This member of the AKAP family, designated mAKAP, anchors both PDE and the regulatory subunit  of PKA to the nuclear membrane, maintaining them in a negative feedback loop that provides close local control of the ATP level and PKA activity.
B- The basal level of PDE activity in the presence of hormone (resting state) keeps cAMP levels below those necessary for PKA activation. 
C- Activation of β-adrenergic receptors causes an increase in cAMP to a level in excess of that which can be degraded by PDE. 
D- The resulting binding of cAMP to the R subunits of PKA releases the active catalytic (C) subunits into the cytosol. Some C subunits enter the nucleus, where they phosphorylate and thus activate certain transcription factors . Other C subunits phosphorylate PDE, stimulating its catalytic activity.
E-  Active PDE hydrolyzes cAMP, thereby driving cAMP levels back to basal levels and causing re-formation of the inactive PKA C-R complex. Subsequent de-phosphorylation of PDE returns the complex to the resting state.

TLS Online TPP Program

#Question id: 15739

#Unit 5. Developmental Biology

 In mammals, If no Y chromosome is present then transcription factors Wt1, Lhx9, GATA4, and Sf1 activate expression of:

TLS Online TPP Program

#Question id: 24171

#General Aptitude

If a car suddenly begins to skid on ice, a driver’s instinctive reaction might be the wrong one.

TLS Online TPP Program

#Question id: 17081

#Unit 12. Applied Biology

What type of drug is Aminopterin and what it is used for