Fever is an abnormal elevation of body temperature. Following statements are regarding to the cellular mechanism of fever.

A. Pyrogens produce fever by increasing the hypothalamic set-point temperature.

B. the mechanism of pyrogen action is increased production of interleukin-1 (IL-1) in phagocytic cells.

C. IL-1 then acts on the anterior hypothalamus to increase local production of prostaglandins, which increase the set-point temperature.

D. IL-1 then acts on the posterior hypothalamus to increase local production of prostaglandins, which increase the set-point temperature.

E. IL-1 then acts on the posterior hypothalamus to increase local production of prostaglandins, which decrease the set-point temperature.

Which of the following combination is correct?

#Question id: 9161

#Unit 9. Diversity of Life Forms

When climbing a mountain, we can observe transitions in biological communities that are analogous to the changes ________.

#Question id: 10961

#Unit 7. System Physiology – Animal

Over the past 12 weeks, a 75-year-old man with a moderate aortic stenosis has developed shortness of breath and chest pains during exertion. He appears pale. Test of his stool for blood is positive. Laboratory studies show the following: hemoglobin 7.2 g/dL, and mean corpuscular volume 75. A blood smear shows microcytic, hypochromic erythrocytes. Which of the following is the most likely diagnosis?

#Question id: 12223

#Unit 10. Ecological Principles

#Question id: 11454

#Unit 7. System Physiology – Animal

The structure of the mammalian middle ear is adapted to convert ________.

#Question id: 1239

#Unit 4. Cell Communication and Cell Signaling

GTPases serve in many signal transduction pathways and the presence of GTP or GDP dictates whether the pathway is on or off, respectively. Which of the following statements is TRUE regarding guanine nucleotide exchange factors (GEF) and the role in these signaling pathways?