TLS Online TPP Program

#Question id: 23327


The problem for the research related to metaphysics can be

#General Aptitude
  1. What is meant by existence
  2. What are the qualities of the existence of the objects
  3. How knowledge of individuality of the objects can be realised
  4. All the above
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TLS Online TPP Program

#Question id: 15365

#Unit 4. Cell Communication and Cell Signaling

The MDM2 protein in its active form can form a complex with p53, inhibiting the transcription factor and causing p53 ubiquitinylation and subsequent proteasomal degradation, ATM phosphorylates MDM2 to inactivate it, causing increased stabilization of p53, but there is one another gene or key regulator which controls the level of MDM2;

TLS Online TPP Program

#Question id: 15364

#Unit 4. Cell Communication and Cell Signaling

In normal cells, FOS and MYC mRNAs and the proteins they encode are intrinsically unstable and degrade rapidly after the genes are transcribed, Conversion of the MYC proto-oncogene into an oncogene can occur by different mechanisms, Other members of this protein set include MAD, MAX, and MNT, choose incorrect statement regarding this,

TLS Online TPP Program

#Question id: 15363

#Unit 4. Cell Communication and Cell Signaling

Epithelial-to-mesenchymal transition (EMT) is thought to play a crucial role during the process of metastasis in some cancers, Snail and Twist are the two transcription factors, function as EXCEPT

TLS Online TPP Program

#Question id: 15362

#Unit 4. Cell Communication and Cell Signaling

Aflatoxin a fungal metabolite found in moldy grains, induces

TLS Online TPP Program

#Question id: 15361

#Unit 4. Cell Communication and Cell Signaling

The chemical benzo(a)pyrene, found in cigarette smoke as well as in coal tar, undergoes metabolic activation in the lungs to form a potent mutagen that mainly, causes conversion of guanine (G) to thymine (T) bases, a transversion mutation, When applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including inactivating mutations of the p53 gene, at codon number______

TLS Online TPP Program

#Question id: 15307

#Unit 4. Cell Communication and Cell Signaling

In attached table some Tumor‐Suppressor Genes are given with their inherited syndrome; select correctly matched genes with their causing syndrome

GeneInherited syndrome
i. TP53Li-Fraumeni syndrome
ii. INK4aFamilial melanoma
iii. PTENFamilial gastric cancer
iv. E-CadherinCowden disease
v. VHLvon Hippel-Lindau syndrome