TLS Online TPP Program

#Question id: 4725


Ptosis (droopy eyelid) may be inherited as a dominant human trait. Among 30 people who are heterozygous for the ptosis allele, 10 have ptosis and 20 have normal eyelids. What is the penetrance for ptosis?

#Unit 8. Inheritance Biology
  1. 50 %       

  2. 33%     

  3. 75%         

  4. 25%

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TLS Online TPP Program

#Question id: 864

#Unit 1. Molecules and their Interaction Relevant to Biology

Which one is not the appropriate function of Heat Shock Proteins;

TLS Online TPP Program

#Question id: 862

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the following

lysosomal protein degradation pathways

         Found in

1. Nonselective

a-well-nourished cells

i-containing the pentapeptide Lys-Phe-Glu-Arg-Gln

2- Selective

b-starving cells

TLS Online TPP Program

#Question id: 861

#Unit 1. Molecules and their Interaction Relevant to Biology

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of

i. Only 2 to 3 minutes,

B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of

ii. >10 hours in prokaryotes

iii. >20 hours in eukaryotes.

TLS Online TPP Program

#Question id: 860

#Unit 1. Molecules and their Interaction Relevant to Biology

Select true ‘T’ AND false ‘F’ about ubiquitinylation

I. These ubiquitin-like modifiers control processes as diverse as nuclear import,

II. Regulated by the ubiquitin-like modifier Sumo, and autophagy,

III. Regulated by the ubiquitin-like modifier Atg8.

IV. For a protein to be efficiently degraded, it must be linked to a chain of at least four tandemly linked ubiquitin molecules in which Lys 34 of each ubiquitin forms an isopeptide bond with the C-terminal carboxyl group of the following ubiquitin.

TLS Online TPP Program

#Question id: 654

#Unit 1. Molecules and their Interaction Relevant to Biology

Which pair represents different conformations?

TLS Online TPP Program

#Question id: 655

#Unit 1. Molecules and their Interaction Relevant to Biology

A change from one conformation of a molecule to another involves ________.