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#Question id: 339


The edges of each base pair are exposed in the major and minor grooves, creating a pattern of hydrogen-bond donors and acceptors and of hydrophobic groups (allowing for Vander Waals interactions) that identifies the base pair. The edge of an C : G base pair displays the following chemical groups in the following order in the major groove:

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. A hydrogen-bond acceptor (at N7 of guanine), a hydrogen-bond acceptor (the carbonyl on C6 of guanine), a hydrogen-bond donor (the exocyclic amino group on C3 of cytosine), and a small nonpolar hydrogen (the hydrogen at C5 of cytosine)

  2. A hydrogen-bond acceptor (at N7 of guanine), a hydrogen-bond acceptor (the carbonyl on C6 of guanine), a hydrogen-bond donor (the exocyclic amino group on C4 of cytosine), and a small nonpolar hydrogen (the hydrogen at C5 of cytosine)

  3. A small nonpolar hydrogen (the hydrogen at C5 of cytosine), a hydrogen-bond donor (the exocyclic amino group on C4 of cytosine), a hydrogen-bond acceptor (the carbonyl on C6 of guanine) and a hydrogen-bond acceptor (at N7 of guanine)

  4. A small nonpolar hydrogen (the hydrogen at C5 of cytosine), a hydrogen-bond acceptor (the exocyclic amino group on C4 of cytosine), a hydrogen-bond acceptor (the carbonyl on C6 of guanine) and a hydrogen-bond donor (at N7 of guanine)

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TLS Online TPP Program

#Question id: 5723

#Unit 8. Inheritance Biology

An individual heterozygous for a reciprocal translocation possesses the following chromosomes

I-  nonviability                                  II – Viability        

III- only translocated chromosome     IV- only normal chromosome

V- one translocated another normal

Which of the following above chromosome constituent and feature in their gamete result from?

A- alternate       B- adjacent-1     C- adjacent-2

TLS Online TPP Program

#Question id: 23966

#Unit 8. Inheritance Biology

Deletion in short arm of chromosome number 4, that leads to cause syndrome;

TLS Online TPP Program

#Question id: 5734

#Unit 8. Inheritance Biology

Following is heterozygote for inversion?

Following some statement given for above abnormality?

A) There is a less probability of a crossover occurring within inversion region and producing an enviable cross over meiotic product.

B) Chromosomes that have engaged in crossing-over separate in the normal fashion, without the creation of a bridge

C) The crossover produces chromatids that contain duplication and a deletion for different parts of the chromosome results non viable gamete

D) Double cross over within inversion loop will be results all viable gamete of parental and recombinant

TLS Online TPP Program

#Question id: 5733

#Unit 8. Inheritance Biology

In individuals heterozygous for a chromosome inversion, the homologous chromosomes form a loop in prophase I of meiosis.

Which of the following is effect of inversion?

A. A dicentric and an acentric chromosome in meiosis I as the chiasmata gets terminated when inversion includes centromere  

B. Appearance of deletion and duplication in both the cross over products chromosomes when centromere outside of inversion region  

C. All recombinant gamete are non-viable gametes when single crossing over within inverted region; irrespective to paracentric or pericentic inversion

D. Nonviable gametes are usually produced, resulting in a depression in observed recombination frequencies.

Which of the above statements are correct?

TLS Online TPP Program

#Question id: 5731

#Unit 8. Inheritance Biology

If an individual is heterozygous for this translocation, the consequence in meiosis will be as follows:

A) Segregation results in a + c in one Gametes and b + d in another gametes, have duplication and deficiency so unable to produce viable offspring

B) Segregation results in a + b in one Gametes and c + d in another gametes, have normal chromosome so all viable offspring produced

C) Segregation results in a + d in one Gametes with normal chromosome and b + c in another gametes contains translocation arrangement, all viable offspring produced

D) Segregation results in a + d in one Gametes with normal chromosome, will produced viable offspring while b + c in another gametes contains translocation arrangement, will produce non viable offspring.

TLS Online TPP Program

#Question id: 5730

#Unit 8. Inheritance Biology

In a family, father is homozygous dominant (AA) for a gene A and his wife is homozygous for its ressive allele (aa) showing albino phenotype. It was surprising that their child showed the albino phenotype. Which of the following phenomenon can explain the phenotype?