#Question id: 14765
#Unit 2. Cellular Organization
#Question id: 4902
#Unit 8. Inheritance Biology
Leber hereditary optic neuropathy (LHON) is mitochondrial diseases present in family. Which of the following observation is correct?
#Question id: 1520
#Unit 1. Molecules and their Interaction Relevant to Biology
Following statements are regarding to enzymatic processing of benzo(a)pyrene to a more potent mutagen and carcinogen.
A. Liver enzymes, particularly P-450 enzymes, modify benzo(a)pyrene in a series of reactions, producing 7,8-diol-9,10-epoxide, a highly potent mutagenic species that reacts with DNA primarily at the N2 atom of a guanine base.
B. The adduct, (+)-trans-anti-B(a)P-N2-dG, causes polymerase to insert an A rather than a C opposite the modified G base. Next time the DNA is replicated, a T will be inserted opposite the A, and the mutation will be complete.
C. Potent mutagen majorly causes conversion of guanine (G) to thymine (T) bases, a transition mutation.
D. When this potent mutagen applied to cultured bronchial epithelial cells, activated benzo(a)pyrene induces many mutations, including activating mutations at codons 175, 248, and 273 of the p53 gene.
Which of the following statements are correct?
#Question id: 12753
#Unit 13. Methods in Biology
#Question id: 682
#Unit 1. Molecules and their Interaction Relevant to Biology
The principle forces holding subunits of an oligomeric protein to each other are ________.