TLS Online TPP Program

#Question id: 542


Hamsters love to run on exercise wheels. Prolonged running at a high rate of speed requires ATP. Could a hamster with a defective gene for the enzyme lactate dehydrogenase meet the extra ATP demand for prolonged, fast wheel-running by maintaining a high rate of glycolysis? Why or why not?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. No, not enough NAD+ can be regenerated for glycolysis to continue at a high rate.

  2. No, the defective gene will cause a rapid decline in pH in the muscles used for running.

  3. Yes, the defective enzyme has no effect on the glycolytic pathway.

  4. Yes, the enzyme alcohol dehydrogenase will supply the needed NAD+ if the lactose dehydrogenase cannot.

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TLS Online TPP Program

#Question id: 1403

#Unit 4. Cell Communication and Cell Signaling

Tumor-suppressor genes encode proteins with which of the following functions?

a. growth-promoting               b. growth-arresting                  c. pro-apoptotic

d. anti-apoptotic                      e. DNA repair

TLS Online TPP Program

#Question id: 1404

#Unit 4. Cell Communication and Cell Signaling

Which of the following are transcription factors?

TLS Online TPP Program

#Question id: 1405

#Unit 4. Cell Communication and Cell Signaling

A gain-of-function mutation in which of the following would have the same effect as a gain-of-function mutation in Ras?

TLS Online TPP Program

#Question id: 1406

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a consequence of p53 stabilization?

a. stabilization of Cdc25A      b. activation of ATM                c. blocked apoptosis

d. transcription of p21                        e. DNA repair

TLS Online TPP Program

#Question id: 1407

#Unit 4. Cell Communication and Cell Signaling

Which of the following is pro-apoptotic?

a. Bax              b. Bcl-2                       c. p53              d. protein kinase B      e. PTEN

TLS Online TPP Program

#Question id: 1409

#Unit 4. Cell Communication and Cell Signaling

Which DNA repair system is affected in patients with xeroderma pigmentosum?