TLS Online TPP Program

#Question id: 801


Identify the type of DNA from the structures given below and match the correct form with its characteristics described.

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. (ii) – The more compact A form of DNA has 11 bp per turn and shows a large tilt of the base pairs with respect to the helix axis.

  2. (i) – The B form, which is observed at high humidity, most closely corresponds to the average structure of DNA under physiological conditions.

  3. (iii) – Z DNA is a left-handed helix and has a zigzag (hence “Z”) appearance and has an anti-conformation of glycosyl bond.

  4. (i) – The A form which is observed under low humidity has a structure similar to the structure that RNA adopts when double-helical.

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TLS Online TPP Program

#Question id: 1402

#Unit 4. Cell Communication and Cell Signaling

Which of the following oncoproteins possess(es) protein kinase activity?

TLS Online TPP Program

#Question id: 1403

#Unit 4. Cell Communication and Cell Signaling

Tumor-suppressor genes encode proteins with which of the following functions?

a. growth-promoting               b. growth-arresting                  c. pro-apoptotic

d. anti-apoptotic                      e. DNA repair

TLS Online TPP Program

#Question id: 1404

#Unit 4. Cell Communication and Cell Signaling

Which of the following are transcription factors?

TLS Online TPP Program

#Question id: 1405

#Unit 4. Cell Communication and Cell Signaling

A gain-of-function mutation in which of the following would have the same effect as a gain-of-function mutation in Ras?

TLS Online TPP Program

#Question id: 1406

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a consequence of p53 stabilization?

a. stabilization of Cdc25A      b. activation of ATM                c. blocked apoptosis

d. transcription of p21                        e. DNA repair

TLS Online TPP Program

#Question id: 1407

#Unit 4. Cell Communication and Cell Signaling

Which of the following is pro-apoptotic?

a. Bax              b. Bcl-2                       c. p53              d. protein kinase B      e. PTEN