TLS Online TPP Program

#Question id: 766


With respect to microRNAs, which, if any, of the following statements, is true?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. MicroRNA is a generic term that covers all tiny RNAs, ones that are less than 35 nucleotides long when mature.

  2. MicroRNA genes often occur in gene clusters within introns of protein-coding genes and are usually transcribed by RNA polymerase II.

  3. MicroRNAs regulate target genes by binding to complementary sequences on one DNA strand of the target gene.

  4. MicroRNAs normally regulate the expression of just a single target gene.

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TLS Online TPP Program

#Question id: 2994

#Unit 2. Cellular Organization

If a cell has completed meiosis I and the first cytokinesis, and is just beginning meiosis II, which of the following is an appropriate description of its genetic contents?

TLS Online TPP Program

#Question id: 2993

#Unit 2. Cellular Organization

During meiosis, a defect occurs in a cell that results in the failure of spindle microtubules binding at the kinetochores. Which of the following statements describes the most likely result of such a defect?

TLS Online TPP Program

#Question id: 2992

#Unit 2. Cellular Organization

DNA was isolated from three different cell types of the same organism, the relative DNA content for each type was determined, and the results were plotted on the graph shown in the figure below. Refer to the graph to answer the following questions. Which sample of DNA might be from a cell that stopped the process of cell division in G0 phase of the cell cycle prior to meiosis?

TLS Online TPP Program

#Question id: 2991

#Unit 2. Cellular Organization

Early observations of a cultured cell line indicated that the cells did not exhibit either density-dependent inhibition or anchorage dependence. What do these observations suggest about this cell line?

TLS Online TPP Program

#Question id: 2990

#Unit 2. Cellular Organization

Mitotic CDK complexes are maintained in an inactive state through inhibitory phosphorylation of the CDK subunit. Two highly conserved tyrosine and threonine residues in mammalian CDKs are subject to regulated phosphorylation.

Gene

  Mutant phenotypes

A. Wee1

i. the cell does not divide but continues to grow

B. CAK kinase

ii. mitotic cyclins are inactivated

C. cdc25 phosphatase

iii. premature entry into mitosis

The following table enlists genes and phenotypes observed on mutation of these genes but not correctly matched. Which one of the following combinations is correctly matched ?

TLS Online TPP Program

#Question id: 2989

#Unit 2. Cellular Organization

Use the figure to answer the question below.

In the figure, G1 is represented by which numbered part(s) of the cycle?