TLS Online TPP Program

#Question id: 892


Assisted protein folding is mediated by a group of proteins known as chaperons, which of the following statements is incorrectly reperesents chaperon activity;

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. chaperon help to fold, unfolded and partially folded polypeptide chains to disrupt the improper association of exposed hydrophobic segments

  2. All molecular chaperones operate by binding to an unfolded or aggregated protein’s, and molecular chaperon donot requires ATP for their activity

  3. molecular chaperones function to lift folding polypeptides out of the false minima in their folding funnels

  4. molecular chaperones were first described as heat shock proteins (Hsp) because their rate of synthesis is increased at elevated temperatures

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TLS Online TPP Program

#Question id: 7282

#Unit 5. Developmental Biology

In humans, neural tube closure defects occur in about 1 in every 1000 live births. Failure to close the neural tube can result from both genetic and environmental causes. A recent report has demonstrated that zinc deficiency disrupts neural tube closure by:

TLS Online TPP Program

#Question id: 7281

#Unit 5. Developmental Biology

Evolutionary conservation of homeotic gene organization and transcriptional expression in fruit flies and mice is seen in the similarity between the Hom-C cluster on Drosophila chromosome 3 and the four Hox gene clusters in the mouse genome.

 

According to this figure, Which of the following statement is correct?

TLS Online TPP Program

#Question id: 7280

#Unit 5. Developmental Biology

In drosophila, Physical forces drive invagination of the ventral furrow. Following statements regarding to this process:

A. The cellularized blastoderm will begin to activate higher levels of myosin in the cells at the ventral midline and preferentially at their apical surface.

B. Epithelial adhesions paired with differential activation of dynein and tissue geometry create mechanical constraints that affect the orientation of actomyosin meshworks.

C. The A/P oriented arrays of myosin in the cells at the ventral midline generate tension along the anterior-posterior axis.

D. The combination of tissue geometry and tension of these anterior-to-posterior meshworks cause the tissue to fold outward at a right angle to the anterior-posterior axis, creating a long and narrow ventral furrow.

Which of the following statements are incorrect?

TLS Online TPP Program

#Question id: 7279

#Unit 5. Developmental Biology

X chromosome number alone is the primary sex determinant in normal drosophila because:

TLS Online TPP Program

#Question id: 7278

#Unit 5. Developmental Biology

The following demonstrates the blastocoel formation in the mammals. Which of the following statement is correct?

TLS Online TPP Program

#Question id: 7277

#Unit 5. Developmental Biology

According to this model, Which of the following statements are correct?