The folding pathways of some proteins require two enzymes that catalyze isomerization reactions such as,

a) Peptide prolyl isomerase (PPI)  catalyzes the elimination of folding intermediates with inappropriate disulfide cross-links

b) Protein disulfide isomerase (PDI) enzyme that catalyzes the interchange, or shuffling, of disulfide bonds until the bonds of the native conformation are formed

c) Peptide prolyl cis-trans isomerase (PPI) catalyzes the interconversion of the cis and trans isomers of Proline residue peptide bonds

d) Peptide prolyl isomerase (PPI) can be a fast step in the folding of proteins that contain some Pro peptide bonds in the cis conformation

Which of the following combinations is correct about protein folding pathways?

TLS Online TPP Program

#Question id: 16310

#Unit 7. System Physiology – Animal

The temperature of the body is regulated almost entirely by nervous feedback mechanisms, and almost all these mechanisms operate through temperature regulating centers located in the hypothalamus. Following statements are as follows:

A. The anterior hypothalamic-preoptic area contains large numbers of heat-sensitive neurons, as well as about one third as many cold-sensitive neurons. These neurons are believed to function as temperature sensors for controlling body temperature.

B. The heat-sensitive neurons increase their firing rate 2- to 10-fold in response to a 10°C increase in body temperature. 

C. The cold-sensitive neurons, by contrast, increase their firing rate when the body temperature increases.

D. Anterior hypothalamus integrates the central and peripheral temperature sensory signals.

Which of the following combination is correct?

TLS Online TPP Program

#Question id: 17077

#Unit 12. Applied Biology

Cells lacking Thymidine kinase if introduced into HAT medium which pathways will continue for nucleotide synthesis

TLS Online TPP Program

#Question id: 15451

#Unit 4. Cell Communication and Cell Signaling

T-cell dependent, B-cell activation require many signals except___

TLS Online TPP Program

#Question id: 9164

#Unit 9. Diversity of Life Forms

Use the following figures to answer the question below.

East of the Mississippi River, in Hopkinsville Kentucky, the mean annual precipitation is 130 cm. The mean annual temperature is 14.3°C. In the winter, the mean temperature is 7.3°C, while in summer it is 20.6°C. Using the climograph shown here, how would we classify the biome found in Hopkinsville?

TLS Online TPP Program

#Question id: 10460

#Unit 6. System Physiology – Plant

CCT overexpression mutant shows____