TLS Online TPP Program

#Question id: 889


The cis and trans GroEL rings undergo conformational changes in a reciprocating fashion, with events in one ring influencing events in the other ring. The entire GroEL/ES chaperonin complex functions as follows;

a) One GroEL ring that has bound 7 ATP also binds an improperly folded substrate protein, which associates with hydrophobic patches that line the inner wall of the GroEL chamber

b) The GroES cap then binds to the GroEL ring like a lid on a pot, inducing a conformational change in the resulting cis ring

c) Within ~10 s the cis ring catalyzes the hydrolysis of its 7 bound ATPs and releases the resulting Pi , which weakens the interactions binding GroES to GroEL

d) A second molecule of improperly folded substrate protein binds to the cis ring, followed by 7 ATP

e) The binding of substrate protein and ATP to the cis ring conformationally induces the trans ring to release its bound GroES, 7 ADP, and the presumably now better-folded substrate protein

Which of the following is incorrect functions of GroEL/ES chaperonin complex?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. B and C        

  2. A, C and E

  3. D and E    

  4. ONLY D

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TLS Online TPP Program

#Question id: 9611

#Unit 9. Diversity of Life Forms

If, someday, an archaean cell is discovered whose SSU-rRNA sequence is more similar to that of humans than the sequence of mouse SSU-rRNA is to that of humans, the best explanation for this apparent discrepancy would be

TLS Online TPP Program

#Question id: 9609

#Unit 9. Diversity of Life Forms

Dozens of potato varieties exist, differing from each other in potato-tuber size, skin color, flesh color, and shape. One might construct a classification of potatoes based on these morphological traits. Which of these criticisms of such a classification scheme is most likely to come from an adherent of the phylocode method of classification?

TLS Online TPP Program

#Question id: 9608

#Unit 9. Diversity of Life Forms

Darwin analogized the effects of evolution as the above-ground portion of a many-branched tree, with extant species being the tips of the twigs. The common ancestor of two species is most analogous to which anatomical tree part?

TLS Online TPP Program

#Question id: 9607

#Unit 9. Diversity of Life Forms

The common housefly belongs to all of the following taxa. Assuming you had access to textbooks or other scientific literature, knowing which of the following should provide you with the most specific information about the common housefly?

TLS Online TPP Program

#Question id: 9604

#Unit 9. Diversity of Life Forms

The various taxonomic levels (viz, genera, classes, etc.) of the hierarchical classification system differ from each other on the basis of

TLS Online TPP Program

#Question id: 9601

#Unit 9. Diversity of Life Forms

The relative lengths of the frog and mouse branches in the phylogenetic tree indicate that