TLS Online TPP Program

#Question id: 861


Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of

i. Only 2 to 3 minutes,

B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of

ii. >10 hours in prokaryotes

iii. >20 hours in eukaryotes.

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. A-II &III

  2. B-II &III

  3. A-I and B-II & III

  4. B-I and A-II & III

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TLS Online TPP Program

#Question id: 4585

#Unit 11. Evolution and Behavior

The cow Bos primigenius (which is bred for meat and milk) has a smaller brain and larger eyes than closely related wild species of ungulates. These traits most likely arose by ________.

TLS Online TPP Program

#Question id: 26508

#Unit 3. Fundamental Processes

Which of the following are true regarding the splicing of tRNA 
a.RnaseP cuts at 5’ end 
b.RnaseD cuts at 3’ end 
c.Base modification followed by CCA addition by specific polymerase
d.And then final script of 78 bp formed

TLS Online TPP Program

#Question id: 10961

#Unit 7. System Physiology – Animal

Over the past 12 weeks, a 75-year-old man with a moderate aortic stenosis has developed shortness of breath and chest pains during exertion. He appears pale. Test of his stool for blood is positive. Laboratory studies show the following: hemoglobin 7.2 g/dL, and mean corpuscular volume 75. A blood smear shows microcytic, hypochromic erythrocytes. Which of the following is the most likely diagnosis?

TLS Online TPP Program

#Question id: 27068

#Unit 1. Molecules and their Interaction Relevant to Biology

Isoleucine and Threonine have two chiral carbons so exists in multiple RS configuration, choose the correct option regarding the given fig.
1. a is D-threonine is (2S, 3S) threonine
2. b is L-threonine is (2R,3S) threonine
3. a is L-threonine is (2S, 3R) threonine
4. b is D-threonine is (2R,3S) threonine

TLS Online TPP Program

#Question id: 11569

#Unit 7. System Physiology – Animal

Oxytocin and antidiuretic hormone (ADH) are synthesized in the ________ but released from the ________.