Following statements are regarding to the formins which involve in filament assembly.A. All formin family members have two adjacent domains in common, the so called FH1 and FH2 domains (formin-homology domains 1 and 2).B. Two FH2 domains from two individual formin monomers associate to form a doughnut-shaped complex can form a dimer and nucleate filament assembly.C. The FH1 domain of formin is rich in proline residues, which serve as sites for the binding of several profilin molecules.D. The FH2 domain behaves as a landing site for profilin–ATP–G-actin to increase the local concentration of these complexes.E. Formins are activated by membrane bound Rho-GTP, a Ras-related small GTPase.Which of the following combination is correct? -triyambak.org