TLS Online TPP Program

#Question id: 14764


Match the following proteins (Column I) with their function (Column II). Which of the following is correct?

Column I

Column II

a. Profilin

i. binds to the (+) end of an actin filament, thereby inhibiting subunit addition or loss.

 

b. Cofilin

ii. blocks (−) ends, inhibits filament disassembly, to stabilize filaments

c. Thymosin-β4

iii. involved in actin treadmilling, but it binds specifically to F-actin in which the subunits contain ADP

d. Cap Z

iv. binds ADP–G-actin and catalyzes the exchange of ADP for ATP

e. Tropomodulin

v. binds to ATP–G-actin in such a way that it inhibits addition of the actin subunit to either end of the filament.

#Unit 2. Cellular Organization
  1. a-i, b-ii, c-v, d-iv, e-iii
  2. a-ii, b-v, c-iv, d-iii, e-i
  3. a-iii, b-ii, c-i, d-iv, e-v
  4. a-iv, b-iii, c-v, d-i, e-ii
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TLS Online TPP Program

#Question id: 2993

#Unit 2. Cellular Organization

During meiosis, a defect occurs in a cell that results in the failure of spindle microtubules binding at the kinetochores. Which of the following statements describes the most likely result of such a defect?

TLS Online TPP Program

#Question id: 2992

#Unit 2. Cellular Organization

DNA was isolated from three different cell types of the same organism, the relative DNA content for each type was determined, and the results were plotted on the graph shown in the figure below. Refer to the graph to answer the following questions. Which sample of DNA might be from a cell that stopped the process of cell division in G0 phase of the cell cycle prior to meiosis?

TLS Online TPP Program

#Question id: 2991

#Unit 2. Cellular Organization

Early observations of a cultured cell line indicated that the cells did not exhibit either density-dependent inhibition or anchorage dependence. What do these observations suggest about this cell line?

TLS Online TPP Program

#Question id: 2990

#Unit 2. Cellular Organization

Mitotic CDK complexes are maintained in an inactive state through inhibitory phosphorylation of the CDK subunit. Two highly conserved tyrosine and threonine residues in mammalian CDKs are subject to regulated phosphorylation.

Gene

  Mutant phenotypes

A. Wee1

i. the cell does not divide but continues to grow

B. CAK kinase

ii. mitotic cyclins are inactivated

C. cdc25 phosphatase

iii. premature entry into mitosis

The following table enlists genes and phenotypes observed on mutation of these genes but not correctly matched. Which one of the following combinations is correctly matched ?

TLS Online TPP Program

#Question id: 2989

#Unit 2. Cellular Organization

Use the figure to answer the question below.

In the figure, G1 is represented by which numbered part(s) of the cycle?

TLS Online TPP Program

#Question id: 2988

#Unit 2. Cellular Organization

Use the figure to answer the question below. 

If the cell whose nuclear material is shown in the figure continues toward completion of mitosis, which of the following events would occur next?