TLS Online TPP Program

#Question id: 12188


The series of events by which APC/C promotes the separation of sister chromatids at anaphase.
A. all the kinetochores have attached to spindle microtubules and the spindle apparatus is properly assembled and oriented.
B. Cdc20 specificity factor associated with APC/C directs it to ubiquitinylate securin and mitotic cyclins. 
C. A protease known as separase cleaves the cohesin subunit Scc1 (Rad21), breaking the protein circles linking sister chromatids.
D. anaphase begins as poleward force exerted on the kinetochores moves the split sister chromatids toward opposite spindle poles.
E. Following securin degradation and a decrease in mitotic CDK activity.
Which of the following series is correct?

#Unit 2. Cellular Organization
  1. AàDàEàCàB
  2. CàBàDàAàE
  3. AàBàEàCàD
  4. AàEàBàCàD