Following statements are regarding to the protein phosphatase Cdc14 function in budding yeast.

A. In budding yeast, the protein phosphatase Cdc14 throws the switch between two mutually antagonistic states during anaphase.

B. Cdc14 is kept inactive during most of the cell cycle, but is activated during anaphase by a GTPase signaling pathway known as the mitotic exit network.

C. Mitotic exit network is unresponsive to spindle position and becomes active in anaphase.

D. Cdc14 phosphatase activated by the activation of protein kinase cascade.

E. Cdc14 dephosphorylates APC/CCdh1 and Sic1 to promote mitotic cyclin degradation

and mitotic CDK inactivation, respectively. This process leads to exit from mitosis.

Which of the following combination is incorrect?

TLS Online TPP Program

#Question id: 15783

#Unit 5. Developmental Biology

During the formation of induced pluripotent stem cell, what is the function of Klf-4?

TLS Online TPP Program

#Question id: 15782

#Unit 5. Developmental Biology

Adult cells may be reprogrammed to gain pluripotency by modifying the genes namely 

TLS Online TPP Program

#Question id: 15781

#Unit 5. Developmental Biology

Chemical regulation of stem cells takes the form of secreted proteins from surrounding cells that influence stem cell states and progenitor differentiation through endocrine, paracrine, or juxtacrine mechanisms. These signaling factors:

TLS Online TPP Program

#Question id: 15780

#Unit 5. Developmental Biology

In drosophila, the somatic cells of the hub are able to regulate stem cell proliferation by secreting the paracrine factor Unpaired onto the cells attached to them. Unpaired activates the JAK-STAT pathway in the adjacent germ stem cells to specify their self-renewal. Those cells that are distant from the paracrine factor cannot receive this signal, they begin their differentiation into the sperm cell lineage. This means hub cells act as

TLS Online TPP Program

#Question id: 15779

#Unit 5. Developmental Biology

During stem cell regulation extracellular mechanisms leading to intracellular changes that regulate stem cell behaviour. Which of the following is not consider as extracellular mechanisms for stem cell regulation?

TLS Online TPP Program

#Question id: 15778

#Unit 5. Developmental Biology

Stem cell regulation is highly influenced by the microenvironment that surrounds a stem cell and is known as the