Many eukaryotic genes contain a large number of exons. Correct splicing of such genes requires that neighboring exons be ligated to one another; if they are not, exons will be left out. One early proposal suggested that the splicing machinery bound to a splice site at one end of an intron and scanned through the intron to find the splice site at the other end. Such a scanning mechanism would guarantee that an exon was never skipped. This hypothesis was tested with one minigene with a duplicated 5ʹ splice site. Find diagram of the products you expect from minigene if the splicing machinery binds to a 5ʹ splice site and scans toward a 3ʹ splice site.

TLS Online TPP Program

#Question id: 15118

#Unit 8. Inheritance Biology

In dominant disorder only normal/affected individuals are appeared in population then what will be the correct expression of Hardy-Weinberg principle

TLS Online TPP Program

#Question id: 15117

#Unit 8. Inheritance Biology

In any population of 10000, in which 100 females were affected from x-linked recessive disorder. What will be the carrier frequency for this x-linked recessive disorder.

TLS Online TPP Program

#Question id: 15005

#Unit 8. Inheritance Biology

You identify a previously unidentified plant species and decide to study its genetics. You establish true breeding strains for leaf shape (longer than wide vs equal length and width) and flower color (white vs. yellow). When you perform a dihybrid cross with these strains, you find that your results are very different than those predicted by a 9:3:3:1 ratio. You calculate a chi square and get a p value of less than 0.0001. Which of the following statements is most accurate based on this observation?

TLS Online TPP Program

#Question id: 15004

#Unit 8. Inheritance Biology

Which of the following statements about a pedigree would be most definitive in determining a recessive pattern of inheritance?

TLS Online TPP Program

#Question id: 15003

#Unit 8. Inheritance Biology

Laurie met her husband Jim at a support group for families dealing with PKU (phenylketonurea), a recessive genetic disorder. Laurie and Jim both have one sister who is affected with PKU and no other family history of the disorder. They come to you as a genetic counselor to ask what their risk is of having an affected child. What do you tell them?

TLS Online TPP Program

#Question id: 12173

#Unit 8. Inheritance Biology

Female with only one X chromosome is a characteristics of individual with