The RNA recognition motif (RRM), also called the RNP motif and the RNA-binding domain (RBD), is the most common RNA-binding domain in hnRNP proteins. Choose important characteristics of RBD

a. RRM domain consists of a four-stranded b sheet flanked on one side by two a helices.

b. To interact with the negatively charged RNA phosphates, the b sheet forms a positively charged surface

c. The 45-residue KH motif is also found in the hnRNP and several other RNA-binding proteins

Which of the following statements are correct?

#Question id: 5752

#Unit 8. Inheritance Biology

#Question id: 5753

#Unit 8. Inheritance Biology

A bacterial histidine mutant was plated on minimal medium and a single colony grew. You decide to sequence the histidine biosynthetic gene of the revertant and discover that the original mutation is still present.  This colony must have been able grow due to a

#Question id: 5754

#Unit 8. Inheritance Biology

A cell is exposed to EMS (a mutagen that causes guanine to mispair with thymine) and allowed to undergo a few rounds of DNA replication.  The mutational event caused by this mutagen will be

#Question id: 5755

#Unit 8. Inheritance Biology

A researcher studying bacterial toxin predicts that a lysine within the toxin is important for binding it’s target cell.  She used site-directed mutagenesis to change a codon for lysine (AAA) to one for asparagine (AAU).  However, the mutant toxin still binds to its target cell just as well as the wild-type toxin bound and appears to have no other changes. This type of mutation is probably

#Question id: 5756

#Unit 8. Inheritance Biology

Type of mutation caused by an addition or deletion of a base in a polypeptide-encoding part of a gene

#Question id: 5758

#Unit 8. Inheritance Biology