The RNA recognition motif (RRM), also called the RNP motif and the RNA-binding domain (RBD), is the most common RNA-binding domain in hnRNP proteins. Choose important characteristics of RBD

a. RRM domain consists of a four-stranded b sheet flanked on one side by two a helices.

b. To interact with the negatively charged RNA phosphates, the b sheet forms a positively charged surface

c. The 45-residue KH motif is also found in the hnRNP and several other RNA-binding proteins

Which of the following statements are correct?

#Question id: 10969

#Unit 7. System Physiology – Animal

Which of the following will result in a transfusion reaction? Assume that the patient has never had a transfusion.

#Question id: 10970

#Unit 7. System Physiology – Animal

A mother of blood type A+ who has always been perfectly healthy just delivered her second child. The father is of blood group O−. Knowing that the child is of blood group O− (O, Rh−), what would you expect to find in this child?

#Question id: 10971

#Unit 7. System Physiology – Animal

A pregnant woman comes in for a visit. She is AB Rh− and her husband is A Rh+. This is her first child. What should be done at this time?

#Question id: 10972

#Unit 7. System Physiology – Animal

What is the proper pathway for the extrinsic clotting pathway?

#Question id: 10973

#Unit 7. System Physiology – Animal

An 11-year-old premenstrual female presents with a painful knee after mild trauma. Upon further evaluation you observe soft tissue bruises. The child is an orphan and there is no family history. The foster mother reports no other problems. The aPTT is prolonged and the PT is normal. A complete hematologic workup would yield

#Question id: 10975

#Unit 7. System Physiology – Animal

A teenaged boy with numerous nosebleeds was referred to a physician for evaluation prior to a minor surgery. His prothrombin time (PT) was 11 sec (11–15 sec normal), partial thromboplastin time (PTT) was 58 sec (25–40 sec normal), and bleeding time was 6.5 min (2–7 min normal). Which of the following is most likely abnormal in this young man?