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TLS Online TPP Program

#Question id: 13162

In the amoeba Dictyostelium discoideum, cAMP acts as an extracellular signalling molecule and binds to and signals via a G protein–coupled receptor; it is not a second messenger. Amoeba cells were transfected with genes encoding two fusion proteins: a Gα fused to cyan fluorescent protein (CFP), and a Gβ fused to yellow fluorescent protein (YFP). CFP normally fluoresces 490-nm light; YFP, 527-nm light. In which conditions fluorescence
energy transfer occur from CFP to YFP?

#Unit 4. Cell Communication and Cell Signaling
  1. If ligand binding occur it leads to association of the Gα and Gβγ subunits, then fluorescence energy transfer can occur.
  2. If ligand binding occur it leads to dissociation of the Gα and Gβγ subunits, then fluorescence energy transfer can occur.
  3. If ligand binding doesn’t occur (In resting state) it leads to dissociation of the Gα and Gβγ subunits, then fluorescence energy transfer can occur.
  4. If ligand binding doesn’t occur (In resting state) it leads to association of the Gα and Gβγ subunits, then fluorescence energy transfer can occur.
     
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TLS Online TPP Program

#Question id: 3542

#Unit 8. Inheritance Biology

All genes are not linked. The probability of a progeny being AaBBccDd from a corss between AABbccDd and aaBBccDD parents will be
TLS Online TPP Program

#Question id: 3545

#Unit 8. Inheritance Biology

Consider the accompanying pedigree of a rare autosomal recessive disease, PKU. Male with PKU marry with normal female whose father is PKU. What is probability of child affected with PKU?
TLS Online TPP Program

#Question id: 4900

#Unit 8. Inheritance Biology

The chlorophyll-deficient types occur in a particular plant species due to a mutation in the DNA of the chloroplast itself, Female cytoplasm chlorophyll-deficient organisms crossed with male normal chlorophyll will produce progeny
TLS Online TPP Program

#Question id: 17809

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. What is the probability that a child will be albino if: Both parents are members of Generation 2, and one parent is albino and the other is non-albino.
TLS Online TPP Program

#Question id: 17808

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. What is the probability that a child will be albino if: One parent is a non-albino member of Generation 2, and the other parent is a non-albino member of Generation 1.
TLS Online TPP Program

#Question id: 17807

#Unit 8. Inheritance Biology

In humans, albinism (unpigmented skin, hair, and eyes) is due to an enzymatic deficiency, and it is an autosomal recessive trait. Suppose that in a small country of one million people (“Generation 1”), there are 500 aa albinos and 9000 Aa heterozygous carriers. What is the probability that a child will be albino if: Both parents are non-albino members of Generation 2?