Following statements are regarding to the phosphoinositide pathway.

A. many activated RTKs and cytokine receptors initiate phosphoinositide pathway by recruiting the enzyme phosphatidylinositol-3 kinase (PI-3 kinase) to the membrane.

B. PI-3 kinase adds a phosphate to the 3′ carbon in one of two separate phosphatidylinositol substrates, leading to formation of two phosphatidylinositol 3-phosphates: PI(3,4)P2 or I(3,4,5)P3

C. PI-3 kinase pathway can trigger cell division and prevent apoptosis, thus ensuring cell survival by the activation of PKB.

D. Activated PKB phosphorylates FOXO3a, which induces the expression of several antiapoptotic genes.

Which of the following combination is correct?

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#Question id: 15779

#Unit 5. Developmental Biology

During stem cell regulation extracellular mechanisms leading to intracellular changes that regulate stem cell behaviour. Which of the following is not consider as extracellular mechanisms for stem cell regulation?

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#Question id: 351

#Unit 1. Molecules and their Interaction Relevant to Biology

 If the cytoplasm of a cell is at pH 7, and the mitochondrial matrix is at pH 8, then the concentration of H+ ions ________.

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#Question id: 4828

#Unit 8. Inheritance Biology

Consider two pairs of alleles, G/g and H/h, that follow complete dominance inheritance. The initial cross consisted of GG hh males and gg HH females, and the F I female progeny were test crossed with gg hh males to produce 380 Gghh progeny out of 1000 total progeny. What is approximate distance between Gene G and H.

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#Question id: 11198

#Unit 7. System Physiology – Animal

The "undershoot" phase of hyperpolarization is due to ________.

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#Question id: 383

#Unit 1. Molecules and their Interaction Relevant to Biology

Three buffers are made by combining a 1 M solution of acetic acid with a 1 M solution of sodium acetate in the ratios shown below

1 M acetic acid	1 M sodium acetate
Buffer 1: 10 mL	90 mL
Buffer 2: 50 mL	50 mL
Buffer 3: 90 mL	10 mL

 Which of these statements is true of the resulting buffers?