Following statements are regarding to the desensitization mechanism of GPCR.

A. Several residues in the cytosolic domain of the β-adrenergic receptor are phosphorylated by the enzyme rhodopsin kinase.

B. β-Arrestin binds to specific phosphorylated tyrosine residues in the C-terminal segment of G protein–coupled receptors (GPCRs).

C. Clathrin and AP2, two other proteins bound by β-arrestin, promote endocytosis of the receptor.

D. β-Arrestin also functions in transducing signals from activated receptors by binding to and activating several cytosolic protein kinases like Src activates the MAP kinase pathway, leading to phosphorylation of key transcription factor.

Which of the following combination is incorrect?

#Question id: 11155

#Unit 9. Diversity of Life Forms

Nucleic acid sequences that undergo few changes over the course of evolutionary time are said to be conserved. Conserved sequences of nucleic acids

#Question id: 11154

#Unit 9. Diversity of Life Forms

Concerning growth in genome size over evolutionary time, which of these does not belong with the others?

#Question id: 11153

#Unit 9. Diversity of Life Forms

A researcher wants to determine the genetic relatedness of several breeds of dog (Canis familiaris). The researcher should compare homologous sequences of __________ that are known to be __________.

#Question id: 11152

#Unit 9. Diversity of Life Forms

When sufficient heat is applied, double-stranded DNA denatures into two single-stranded molecules as the heat breaks all of the hydrogen bonds. In an experiment, molecules of single-stranded DNA from species X are separately hybridized with putatively homologous single-stranded DNA molecules from five species (A-E). The hybridized DNAs are then heated, and the temperature at which complete denaturation occurs is recorded. Based on the data below, which species is probably most closely related to species X?

#Question id: 11151

#Unit 9. Diversity of Life Forms

What conclusion can be drawn validly from these data?

#Question id: 11124

#Unit 9. Diversity of Life Forms

A researcher compared the nucleotide sequences of a homologous gene from five different species of mammals with the homologous human gene. The sequence homology between each speciesʹ version of the gene and the human gene is presented as a percentage of similarity.

What probably explains the inclusion of rabbits in this research?