Following statements are regarding to the phosphoinositide signaling pathway.

A. Many RTKs and cytokine receptors can initiate the IP3/ DAG signaling pathway by activating phospholipase Cβ (PLCβ), a different PLC isoform.

B. Activated RTKs and cytokine receptors also can initiate another phosphoinositide pathway by binding a PI-3 kinase, thereby allowing the enzyme access to its membrane-bound phosphoinositide substrates, which then become phosphorylated at the 3 position.

C. Protein kinase B (PKB) becomes partially activated by binding to PI 3-phosphates with its PH domain.

D. Full activation of PKB requires phosphorylation by the kinase PDK1, which is also recruited to the membrane by binding to PI 3-kinase, and by a second kinase, PDK2.

Which of the following combination is incorrect?

#Question id: 5661

#Unit 5. Developmental Biology

Following statements regarding to the embryogenesis in A. thaliana.

A. The first zygotic division is unequal, with the basal cell larger than the apical cell. The basal cell divides to give rise to the suspensor. The apical cell divides vertically to form a two-celled proembryo, which will give rise to the rest of the embryo.

B. The top most suspensor cell is recruited into the embryo, where it is known as the hypophysis, and contributes to the embryonic root meristem and root cap.

C. The next two divisions produce an eight-cell octant-stage embryo, which develops into a heart-stage embryo of around 32 cells

D. The embryo elongates and the cotyledons start to develop as wing-like structures at one end, while an embryonic root forms at the other. This stage is known as the globular stage.

Which of the following statements are correct?

#Question id: 5553

#Unit 5. Developmental Biology

The notochord is a ___ structure in vertebrate embryos that lies under the ___, and is bordered by ___.

#Question id: 23197

#Unit 13. Methods in Biology

#Question id: 24028

#General Aptitude

#Question id: 23444

#Unit 1. Molecules and their Interaction Relevant to Biology