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TLS Online TPP Program

#Question id: 1239

GTPases serve in many signal transduction pathways and the presence of GTP or GDP dictates whether the pathway is on or off, respectively. Which of the following statements is TRUE regarding guanine nucleotide exchange factors (GEF) and the role in these signaling pathways?

#Unit 4. Cell Communication and Cell Signaling

  1. They hydrolyze GTP into GDP and Pi.

  2. They decrease the GTPase activity of the G-protein.

  3. They catalyze the dissociation of GDP on the G-protein and promote the replacement of GTP.

  4. They catalyze the dissociation of GTP on the G-protein and promote the replacement of GDP.

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TLS Online TPP Program

#Question id: 5344

#Unit 8. Inheritance Biology

What is the most probable mode of inheritance depicted in the following pedigree?
TLS Online TPP Program

#Question id: 5345

#Unit 8. Inheritance Biology

Which of the following above is most probable mode of inheritance?
TLS Online TPP Program

#Question id: 5346

#Unit 8. Inheritance Biology

The following typical pedigree illustrates the key point that affected children are born to unaffected parents: Which of the following is correct statement?
TLS Online TPP Program

#Question id: 5347

#Unit 8. Inheritance Biology

The inheritance of a given disorder is recorded in small families shown below: Based on the above limited information, which one of the following inheritance pattern best explains the observations?
TLS Online TPP Program

#Question id: 5363

#Unit 8. Inheritance Biology

A Southern blot using a probe that binds to the region spanning the mutation causing albinism detects one DNA fragment in homozygous normal individuals (A/A) and two fragments in albino individuals (a/a). Following banding pattern of three offspring of parents? Which of the following correct regarding parents?
TLS Online TPP Program

#Question id: 5357

#Unit 8. Inheritance Biology

This pedigree shows the inheritance of a recessive trait in humans. Individuals that have the trait are homozygous for a recessive allele a. If H and I, who happen to be first cousins, marry and have a child, what is the chance that this child will have the recessive trait?