The transformation of a normal cell to a cancer cell is accompanied  by the loss of function of one or more tumor‐suppressor genes. High‐throughput sequencing studies have identified hundreds of genes that are implicated as tumor suppressors in humans. Some of the better characterized genes;

Gene	Primary tumor	Proposed function
i) APC	Colorectal	Binds β ‐catenin acting as transcription factor
ii) BRCA1	Breast	DNA repair
iii) MSH2, MLH1	Melanoma, pancreatic	p16: Cdk inhibitor ARF: stabilizes p53
iv) E‐Cadherin	Breast, colon	Cell adhesion molecule
v) INK4a	Colorectal	Mismatch repair
vi) NF1	Neurofibromas	Activates GTPase of Ras

Choose incorrect matching regarding tumor‐suppressor genes/primary tumor/proposed functions;

TLS Online TPP Program

#Question id: 13227

#Unit 6. System Physiology – Plant

Match the following  Special Techniques Are Used in Nutritional Studies;

Which of the following combination is correct ?

TLS Online TPP Program

#Question id: 13226

#Unit 6. System Physiology – Plant

Mengel and Kirkby  have proposed that the essential elements be classified instead according to their biochemical role and physiological function, It shows such a classification, in which plant nutrients have been divided into some basic groups these are;

a.) The first group is nutrients that are part of carbon compounds

b.) The second group is important in energy storage reactions or in maintaining structural integrity

c.) The third group has important roles in reactions involving electron transfer or redox reaction

d.) The fourth group is present in plant tissue as either free ions or ions bound 

Which one of the following group represents CORRECT statements

TLS Online TPP Program

#Question id: 13225

#Unit 6. System Physiology – Plant

 The three elements are not considered mineral nutrients these are-

TLS Online TPP Program

#Question id: 13224

#Unit 6. System Physiology – Plant

Suberin is

TLS Online TPP Program

#Question id: 13223

#Unit 6. System Physiology – Plant

At the endodermis, which pathway is blocked by the Casparian strip

TLS Online TPP Program

#Question id: 13222

#Unit 6. System Physiology – Plant

More mature regions of the root often have an outer layer of protective tissue, called an