TLS Online TPP Program

#Question id: 1536


Use the following figure to answer the question. According to figure, which of the following statement is incorrect?

#Unit 4. Cell Communication and Cell Signaling
  1. Tumors as well as normal tissues are likely to consist of small number of stem cells that have self-renewal capability and multipotentiality, precursor cells that have limited proliferative potency, and differentiated cells.

  2. Cancer stem cells are thought to be transformed from tissue specific stem cells, precursor cells and/or differentiated cells by genetic/epigenetic mutations.

  3. Cancer stem cells exist in special microenvironment “niche” and seem to keep their resistance to a variety of anti-cancer treatment methods.

  4. Cancer stem cells do not need microenvironment (hypoxic) for the maintenance of stemness, tumorigenesis, and resistance to anti-cancer treatments, chemotherapy and irradiation.

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TLS Online TPP Program

#Question id: 2992

#Unit 2. Cellular Organization

DNA was isolated from three different cell types of the same organism, the relative DNA content for each type was determined, and the results were plotted on the graph shown in the figure below. Refer to the graph to answer the following questions. Which sample of DNA might be from a cell that stopped the process of cell division in G0 phase of the cell cycle prior to meiosis?

TLS Online TPP Program

#Question id: 2991

#Unit 2. Cellular Organization

Early observations of a cultured cell line indicated that the cells did not exhibit either density-dependent inhibition or anchorage dependence. What do these observations suggest about this cell line?

TLS Online TPP Program

#Question id: 2990

#Unit 2. Cellular Organization

Mitotic CDK complexes are maintained in an inactive state through inhibitory phosphorylation of the CDK subunit. Two highly conserved tyrosine and threonine residues in mammalian CDKs are subject to regulated phosphorylation.

Gene

  Mutant phenotypes

A. Wee1

i. the cell does not divide but continues to grow

B. CAK kinase

ii. mitotic cyclins are inactivated

C. cdc25 phosphatase

iii. premature entry into mitosis

The following table enlists genes and phenotypes observed on mutation of these genes but not correctly matched. Which one of the following combinations is correctly matched ?

TLS Online TPP Program

#Question id: 2989

#Unit 2. Cellular Organization

Use the figure to answer the question below.

In the figure, G1 is represented by which numbered part(s) of the cycle?

TLS Online TPP Program

#Question id: 2988

#Unit 2. Cellular Organization

Use the figure to answer the question below. 

If the cell whose nuclear material is shown in the figure continues toward completion of mitosis, which of the following events would occur next?

TLS Online TPP Program

#Question id: 2987

#Unit 2. Cellular Organization

Following statements are regarding the goals of gap phases.

(i) to prepare for the next phase of the cell cycle.

(ii) to check that the previous phase of the cell cycle has been completed appropriately.

(iii) to inhibits CDKs activity.

(iv) to enhance servillance mechanisms.

Which of the following is correct?