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TLS Online TPP Program

#Question id: 1528

Mutation of p53 is described as a dominant-negative mutation. Which of the following statement is correct regarding to the mechanism by which this mutation causes the dominant-negative phenotype?

#Unit 4. Cell Communication and Cell Signaling

  1. Mutation of p53 is a dominant-negative mutation because the active protein is a dimer of identical subunits; the presence of even one defective subunit in the complex abrogates its function.

  2. Mutation of p53 is a dominant-negative mutation because the active protein is a pentamer of identical subunits; the presence of even one defective subunit in the complex abrogates its function.

  3. Mutation of p53 is a dominant-negative mutation because the active protein is a tetramer of identical subunits; the presence of even one defective subunit in the complex abrogates its function.

  4. Mutation of p53 is a dominant-negative mutation because the active protein is a heptamer of identical subunits; the presence of even one defective subunit in the complex abrogates its function.

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TLS Online TPP Program

#Question id: 3859

#Unit 3. Fundamental Processes

Polyadenylation is:
TLS Online TPP Program

#Question id: 12971

#Unit 10. Ecological Principles

One group of ecologists has suggested that producers are limited by competition for resources, primary consumers (herbivores) are limited by predation, and secondary consumers (carnivores) are limited by food. If this were true, at which of the following trophic levels would one expect to find substantial evidence for competitive exclusion?
TLS Online TPP Program

#Question id: 11430

#Unit 2. Cellular Organization

For GLUT1 in the human erythrocyte membrane, the Km for glucose transport is 1.5 mM. Thus when the extracellular glucose concentration is 1.5 mM, roughly half the GLUT1 transporters with outward-facing binding sites will have a bound glucose, and transport will occur:
TLS Online TPP Program

#Question id: 23915

#General Aptitude

According to the Botanical Survey of India, the total number of plant species in India is about:
TLS Online TPP Program

#Question id: 8950

#Unit 9. Diversity of Life Forms

You have before you a living organism, which you examine carefully. Which of the following should convince you that the organism is acoelomate?