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TLS Online TPP Program

#Question id: 1525

Following statements are regarding to chromatin remodelling factors SWI/SNF complexes. Which one of them is incorrect?

#Unit 4. Cell Communication and Cell Signaling

  1. SWI/SNF complexes large and diverse multiprotein complexes, which have an ATP-dependent helicase at their core, often control histone modification and chromatin remodeling.

  2. SWI/SNF complexes can cause changes in the positions or structures of nucleosomes, making genes accessible or inaccessible to DNA-binding proteins that control transcription.

  3. SWI/SNF plays a role in repressing the expression of E2F genes, thereby inhibiting progression through the cell cycle.

  4. Loss of SWI/SNF function, just like gain of Rb function, can lead to overgrowth and tumor formation.

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TLS Online TPP Program

#Question id: 4725

#Unit 7. System Physiology – Animal

Ptosis (droopy eyelid) may be inherited as a dominant human trait. Among 30 people who are heterozygous for the ptosis allele, 10 have ptosis and 20 have normal eyelids. What is the penetrance for ptosis?
TLS Online TPP Program

#Question id: 19129

#Unit 12. Applied Biology

Physical components in a biosensor include
TLS Online TPP Program

#Question id: 11088

#Unit 7. System Physiology – Animal

At a fraternity party a 17-year-old male places a paper bag over his mouth and breathes in and out of the bag. As he continues to breathe into this bag, his rate of breathing continues to increase. Which of the following is responsible for the increased ventilation?
TLS Online TPP Program

#Question id: 1518

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to the some cancers harbor characteristic chromosome alterations. Chronic myelogenous leukemia (CML), a common leukemia in humans, was found to be associated with the Philadelphia chromosome.

A. Philadelphia chromosome is generated by a translocation between chromosomes 22 and 9. The two chromosomes exchange their terminal regions, which leads to a characteristic alteration in the size of chromosome 9.

B. At the breakpoint of this translocation, a new fusion protein, the BCR-ABL fusion, is generated.

C. The BCR-ABL fusion protein is a constitutively active kinase that phosphorylates multiple signal-transducing proteins.

D. If this translocation occurs in a hematopoietic cell in the bone marrow, the activity of the chimeric BCR-ABL oncogene dephosphorylate proteins thereby activating many intracellular signal-transducing proteins.

Which of the following statements are incorrect?
TLS Online TPP Program

#Question id: 10373

#Unit 6. System Physiology – Plant

The nodulation (nod) genes are classified as common nod genes or host specific nod genes. Some statements related to such classification are given below;

a) nod A is a common nod gene and nod Q is a host specific gene

b) nod B is a common nod gene and nod C is a host specific gene

c) nod C is a common nod gene and nod H is a host specific gene

d) nod H is a common nod gene and nod P is a host specific gene

Choose the correct answer from the above statements: