we examine how the deregulation of growth-promoting and growth-inhibiting signaling pathways contributes to tumorigenesis. Mutations-

A. A mutation that alters a single amino acid (valine to glutamine) in the transmembrane region of the HER2 receptor

B. A deletion that causes loss of the extracellular ligand-binding domain in the EGF receptor Results-

i. dimerization of the receptor, even in the absence of the normal EGF-related ligand, transforming it into the oncoprotein, a constitutively active kinase

ii. to constitutive activation of the kinase activity of the resulting oncoprotein

iii. no dimerization, even in the presence of the normal EGF-related ligand, repression of kinase activity

which of the following results are displayed after these mutations?

TLS Online TPP Program

#Question id: 23987

#Unit 1. Molecules and their Interaction Relevant to Biology

If there is a great problem of discipline in your school which disrupts the routine of the school. What would you like to do to deal with such a utter chaos?

TLS Online TPP Program

#Question id: 23988

#Unit 1. Molecules and their Interaction Relevant to Biology

Suppose luckily you get an opportunity to serve the minority institution. The castism and narrow views are the rules of the place. As you are little bit having scientific outlook and you become prey of victimisation. How would you find yourself in a equilibrium in such an institution?

TLS Online TPP Program

#Question id: 23989

#Unit 1. Molecules and their Interaction Relevant to Biology

If your principal indulges in corruption and forces you to co-operate, how would you make compromise with such a superior fellow?

TLS Online TPP Program

#Question id: 809

#Unit 1. Molecules and their Interaction Relevant to Biology

A single-stranded DNA molecule contains 40 nucleotides with equal amounts of A, C, G, and T. This DNA strand can combine with a complementary DNA strand to form a double-stranded DNA molecule. Which of the following double-stranded DNA molecules would denature at a lower temperature than the 40 base-pair double-stranded molecule described above?

TLS Online TPP Program

#Question id: 808

#Unit 1. Molecules and their Interaction Relevant to Biology

Which, if any, of the following statements is false?

TLS Online TPP Program

#Question id: 807

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following forces can stabilize a normal DNA double-helix?