Stage thymocytes express neither CD4 nor CD8, markers associated with mature T cells. They are therefore called double negative (DN) cells. DN cells first travel to the region under the thymic capsule, a region referred to as the ________, where they proliferate and begin to generate their T-cell receptors. Thymocytes that successfully express TCRs begin to express both CD4 and CD8, becoming double positive (DP) cells, and populate the cortex, the site where most (85% or more) immature T cells are found.

TLS Online TPP Program

#Question id: 7315

#Unit 5. Developmental Biology

Following pathway represents apoptosis in drosophila. Identify the proteins A-D sequentially.

TLS Online TPP Program

#Question id: 7316

#Unit 5. Developmental Biology

Programmed cell death, or apoptosis, is an essential part of animal development. In the nematode, with its invariant cell lineage, particular cell lineages or particular cells within specific lineages are destined to end in programmed cell death, and it was this feature that allowed the identification of the process and the analysis of its genetic control.

Which of the following combination of genes are correct?

TLS Online TPP Program

#Question id: 7754

#Unit 5. Developmental Biology

In autophagy, the endoplasmic reticulum (ER) first gives rise to a cup-shaped, membranous cisterna called the

TLS Online TPP Program

#Question id: 7755

#Unit 5. Developmental Biology

which type of complex is required for movement of ATG9 from the phagophore assembly site to the peripheral site, where it obtains fresh membrane?

TLS Online TPP Program

#Question id: 7757

#Unit 5. Developmental Biology

The TOR (target of rapamycin) kinase complex acts as a

TLS Online TPP Program

#Question id: 7761

#Unit 5. Developmental Biology

Correct sets of genes are well known to be involved in aging and its prevention, and each set appears to be conserved between phyla and even kingdoms. 

a. DNA repair enzymes

b. proteins of the insulin signaling pathway

c. proteins in the mTORC1 signaling pathway

d. chromatin remodeling enzymes