TLS Online TPP Program

#Question id: 15419


Doris Taylor’s research group used detergents to remove all the cells from a cadaveric rat heart, which leaves behind the natural extracellular matrix. An extracellular matrix scaffold can promote the differentiation and rebuilding of a beating heart. The researchers then infused this ECM scaffold with cardiomyocytes. Now these cells differentiated and organized into a functionally contracting “recellularized” heart. Which of the following statement is correct?

#Unit 5. Developmental Biology
  1. The decellularized ECM were instructive in allowing the cardiomyocytes to recreate contracting heart muscle.
  2. The decellularized ECM were permissive in allowing the cardiomyocytes to recreate contracting heart muscle.
  3. The decellularized ECM were permissive and instructive both & allowing the cardiomyocytes to recreate contracting heart muscle.
  4. The decellularized ECM were involve in Epithelial-mesenchymal interaction to allowing the cardiomyocytes to recreate contracting heart muscle.