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#Question id: 5685


Human sperm are allowed to fertilize ova having non- functional ovastacin. The following possibilities may be of significance in the fusion of these gametes:

A.        The sperms will not fertilize ova.

B.        The sperms will bind and penetrate the zona pellucida but will not be able to fuse with ovum membrane.

C.        ZP2 will not be clipped by cortical granule protease.

D.        CD9 protein of egg membrane microvilli will not be able to interact sperm membrane proteins in the absence of ovastacin.

E.         Polyspermy may occur frequently.

Which combination of statements represent the outcome of the above event?

#Unit 5. Developmental Biology
  1. A and B

  2. C and D

  3. C and E

  4. B and C

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TLS Online TPP Program

#Question id: 10298

#Unit 6. System Physiology – Plant

Wernicke-Korsakoff syndrome is more common among people with alcoholism than in the general population, The syndrome can be exacerbated by a mutation in the gene for;

TLS Online TPP Program

#Question id: 10297

#Unit 6. System Physiology – Plant

The following statements are related to pentose phosphate pathway.

a) The first and third steps are oxidations with large, negative standard free-energy changes and are essentially irreversible in the cell

b) NADPH rises and inhibits the first enzyme in the pentose phosphate pathway. As a result, more glucose 6-phosphate is available for glycolysis

c) All the enzymes of the reversible reaction of the pentose phosphate pathway are located in the cytosol

d) The NADPH is used for biosynthetic reactions such as lipid synthesis and nitrogen assimilation in the cytosol

which one of the following combination  of above statements is incorrect?

TLS Online TPP Program

#Question id: 10295

#Unit 6. System Physiology – Plant

Reactions of the pentose phosphate pathway regeneration run six turns of this cycle, what will be predict after that?

TLS Online TPP Program

#Question id: 10289

#Unit 6. System Physiology – Plant

If C6 of glucose is radiolabelled, which carbon of Dihydroxyacetone phosphate and glyceraldehyde 3-phosphate  is radiolabelled?

TLS Online TPP Program

#Question id: 10288

#Unit 6. System Physiology – Plant

 If all the ATP are radiolabelled in the cytosol, then predict about radioactivity of each compound.

 a) All enzyme  of glycolysis will be radiolabelled except 2-phophoglycerate and phosphenol pyruvate

 b) 2-phophoglycerate and phosphenol pyruvate are radiolabelled only the next cycle of glycolysis after cytosolic ATP radiolabelling

 c) 1,3 bisphosphoglycerate will be radiolabelled at 1 and 3 both position

 d) 2-phosphoglycerate are not radiolabelled because its enzyme phosphoglycerate mutase active site contain histidine residue exchange phosphate group from 3-phosphoglycerate

 which prediction about radiolabelling is incorrect?

TLS Online TPP Program

#Question id: 10287

#Unit 6. System Physiology – Plant

Glyceraldehyde 3-phosphate dehydrogenase avtive site contain