TLS Online TPP Program

#Question id: 5667


There may be an important connection between sperm translocation and capacitation. Which of the following option is correct explanation of above statement?

#Unit 5. Developmental Biology
  1. The influx of bicarbonate ions (and possibly other ions) alkalinizes the sperm, raising its pH.

  2. before entering the ampulla of the oviduct, the uncapacitated sperm bind actively to the membranes of the oviduct cells in the narrow passage (the isthmus) preceding it.  This binding is temporary and appears to be broken when the sperm become capacitated.

  3. The cholesterol efflux from the sperm cell membrane is thought to change the location of its “lipid rafts,” isolated regions that often contain receptor proteins that can bind the zona pellucida and participate in the acrosome reaction.

  4. Capacitation is a transient event but translocation is not