Following statements are regarding to the drosophila.

 A. At the completion of oogenesis, the bicoid message is anchored at the anterior end of the oocyte and the nanos message is tethered to the posterior end in translationally dormant condition.

 B. The translation inhibitors Smaug and CUP. Smaug binds to the 3’UTR of both bicoid and nanos mRNA and recruits the CUP protein that prevents the association of the message with the ribosome as well as recruiting other proteins that deadenylate the message and target it for degradation.

 C. The bicoid-Exuperantia complex is transported out of the nurse cells and into the oocyte via microtubules (Kinesin ATPase).

 D. Two other maternally provided mRNAs—caudal and hunchback are critical for patterning the anterior and posterior regions of the body plan, respectively.

 Which of the following combination is correct?

TLS Online TPP Program

#Question id: 26508

#Unit 3. Fundamental Processes

Which of the following are true regarding the splicing of tRNA 

a.RnaseP cuts at 5’ end 

b.RnaseD cuts at 3’ end 

c.Base modification followed by CCA addition by specific polymerase

d.And then final script of 78 bp formed

TLS Online TPP Program

#Question id: 26507

#Unit 3. Fundamental Processes

Which of the compound are shown below

TLS Online TPP Program

#Question id: 26505

#Unit 3. Fundamental Processes

Which of the splicing snRNPs is common in both major and minor

TLS Online TPP Program

#Question id: 26504

#Unit 3. Fundamental Processes

SR proteins are involved in exon definition in which they interact with U1 and U2AF forming the commitment for

TLS Online TPP Program

#Question id: 26503

#Unit 3. Fundamental Processes

Match the following

Protein	Function
1. Prp 5	a. helps the release of the mature mRNA from the spliceosome
2. Brr 2	b. is responsible for the activation of the spliceosome
3. Prp 2	c. facilitates U1 and U4 release
4. Prp 22	d. is critical for U2 binding

TLS Online TPP Program

#Question id: 26502

#Unit 3. Fundamental Processes

Splice sites are directional in nature. 5’ splice site -the left, or donor, site and the 3’ splice site - right, or acceptor, site. So, in below table the complex and their events are given match them correctly .

Column 1	Column 2
1. E complex	a. Joining of U4/6 and U5 tri-snRNPs
2. A complex	b. U2 addition to base pair with the branch site in the presence of ATP
3. B1 complex	c. Formation of commitment complex in which U1 is base paired with the 5' splice site