The enzyme aldolase, catalyzes a reversible aldol condensation, Fructose 1,6-bisphosphate is cleaved to yield two different triose phosphates, glyceraldehyde 3-phosphate, an aldose, and dihydroxyacetone phosphate, a ketose. There are two classes of aldolases such as;

A) Class I aldolases

B) Class II aldolases

i) Found in animals and plants

ii) Found in in fungi and bacteria

iii) formation of protonated Schiff base on enzyme and its active site contain lysine residue

iv) do not form the Schiff base intermediate and a zinc ion at the active site is coordinated with the carbonyl oxygen at C-2

In which of the following option is the given enzyme with its correct statements?

TLS Online TPP Program

#Question id: 12178

#Unit 2. Cellular Organization

Following statements are regarding to V-class ATPases.

A. An organelle lumen or an extracellular space to become acidic, movement of protons must be accompanied by movement of an equal number of anions (e.g., Cl−) in the same direction.

B. An organelle lumen or an extracellular space to become acidic, movement of protons must be accompanied by movement of equal numbers of a different cation in the same direction.

C. An organelle lumen or an extracellular space to become acidic, movement of protons must be accompanied by movement of equal numbers of a different cation in the opposite direction.

D. An organelle lumen or an extracellular space to become acidic, movement of protons must be accompanied by movement of an equal number of anions (e.g., Cl−) in the opposite direction.

Which of the following combination is correct?

TLS Online TPP Program

#Question id: 12177

#Unit 2. Cellular Organization

Calculate the free energy required to move 1 mol of K+ ions from the outside of the cell (where [K+] = 4 mM) to the inside (where [K+] = 140 mM) when the membrane potential is –70 mV and the temperature is 37°C.

TLS Online TPP Program

#Question id: 11523

#Unit 2. Cellular Organization

In the given figure, which of the following complex represents high energy intermediate?

TLS Online TPP Program

#Question id: 11522

#Unit 2. Cellular Organization

What is the major function of the actuator domain in Na+-K+ ATPase?

TLS Online TPP Program

#Question id: 11521

#Unit 2. Cellular Organization

The Na+-K+ ATPase is responsible for maintaining:

TLS Online TPP Program

#Question id: 11520

#Unit 2. Cellular Organization

For the SERCA pump, how many Ca2+ ions moves across the membrane during each catalytic cycle ?