Each of the nine glycolytic intermediates between glucose and pyruvate is phosphorylated. The phosphoryl groups seem to have many functions such as,

a) The plasma membrane generally lacks transporters for phosphorylated sugars, the phosphorylated glycolytic intermediates cannot leave the cell

b) After the initial phosphorylation, further energy is necessary to retain phosphorylated intermediates in the cell, despite the large difference in their intracellular and extracellular concentrations

c) Phosphoryl groups are essential components in the enzymatic conservation of metabolic energy, Energy released in the breakage of phosphoanhydride bonds is partially conserved in the formation of phosphate esters such as glucose 6-phosphate

d) Binding energy resulting from the binding of phosphate groups to the active sites of enzymes lowers the activation energy and increases the specificity of the enzymatic reactions

which of the following functions shows Importance of Phosphorylated Intermediates?

TLS Online TPP Program

#Question id: 13001

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is incorrect 

a) antiparallel β sheets are frequently found and they are quite more stable because of more no. hydrogen bond presence and linear H bonding pattern.

b) antiparallel β sheets are frequently found and they are quite more stable because of more no. hydrogen bond presence and having distorted H bonding pattern.

c) parallel β sheets are relatively less stable and mostly found in core of protein.

d) parallel β sheets are relatively more stable and mostly found in core of protein.

TLS Online TPP Program

#Question id: 13000

#Unit 1. Molecules and their Interaction Relevant to Biology

Identify the correct statement regarding the structure

TLS Online TPP Program

#Question id: 12999

#Unit 1. Molecules and their Interaction Relevant to Biology

Proline and glycine both disturb the symmetry of α-helix which of the following are true regarding to these two amino acids

a) proline changes the orientation of hetropolymeric α-helix hence proline can be placed only as 1st amino acid residue near to C-terminus 

b) proline changes the orientation of polymeric α-helix hence proline can be placed only as 1st amino acid residue near to N-terminus

c) glycine disrupts the heteropolymeric α-helix by changing the helicity.

d) homopolymer of proline and glycine can form stable helix. 

TLS Online TPP Program

#Question id: 12998

#Unit 1. Molecules and their Interaction Relevant to Biology

Match with appropriate bonding pattern

TLS Online TPP Program

#Question id: 12997

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the given reason is correct to minimize the repulsion in an α-helix

a) positively charged amino acids are often found near the amino terminus of the helical segment

b) negatively charged amino acids are often found near the amino terminus of the helical segment

c) positively charged amino acids are often found near the C-terminus of the helical segment.

d) negatively charged amino acids are often found near the C-terminus of the helical segment.

TLS Online TPP Program

#Question id: 12996

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is incorrect regarding to α-helix

a) In the α helix, the first four NH groups and last four CO groups will normally lack backbone  hydrogen bonds.

b) the length of an amino acid in α-helix reduced almost 3 times than linear structure.

c) the frequent occurrence of Pro and Gly residues favour α-helix formation.

d) dihedral (ϕ and ψ) angle should be close to -57 and -47.