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TLS Online TPP Program

#Question id: 10275

In the initial phase of glycolysis, each hexose unit is phosphorylated twice and then split, producing two molecules of triose phosphate, in these reactions included irreversible reaction. How much irreversible reaction is performed in the glycolytic pathway through in this series of reactions?

#Unit 6. System Physiology – Plant
  1. Include two of the three essentially irreversible reactions of the glycolytic pathway, which are catalyzed by hexokinase and phosphofructokinase
  2. Include two of the four essentially irreversible reaction, catalyzed by phosphohexose isomerase and aldolase
  3. Include two of the three essentially irreversible reactions, catalyzed by phosphohexose isomerase and phosphofructokinase
  4. Include two of the three essentially irreversible reactions, catalyzed by Triose phosphate isomerase and aldolase
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TLS Online TPP Program

#Question id: 867

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the correct diseases with their precursors

DiseaseProtein or precursor involved in disease
1. Cystic fibrosisa. Prion protein
2. Creutzfeldt–Jakob diseaseb. CFTR
3. Familial hypercholesterolaemiac. LDL receptor
4. fatal familial insomniad. β-amyloid protein
5. Alzheimer's diseasee. β-hexosaminidase
TLS Online TPP Program

#Question id: 865

#Unit 1. Molecules and their Interaction Relevant to Biology

In autophagy, the endoplasmic reticulum (ER) first gives rise to a cup-shaped, membranous cisterna called the______
TLS Online TPP Program

#Question id: 864

#Unit 1. Molecules and their Interaction Relevant to Biology

Which one is not the appropriate function of Heat Shock Proteins;
TLS Online TPP Program

#Question id: 862

#Unit 1. Molecules and their Interaction Relevant to Biology

Match the following

lysosomal protein degradation pathwaysFound in
1. Nonselectivea-well-nourished cells

i-containing the pentapeptide

Lys-Phe-Glu-Arg-Gln

2- Selectiveb-starving cells
TLS Online TPP Program

#Question id: 861

#Unit 1. Molecules and their Interaction Relevant to Biology

Alexander Varshavsky discovered, the half-lives of many cytoplasmic proteins vary with the identities of their N-terminal residues via the so-called N-end rule:-

A. Destabilizing N-terminal residues Asp, Arg, Leu, Lys, and Phe have half-lives of

i. Only 2 to 3 minutes,

B. Stabilizing N-terminal residues Ala, Gly, Met, Ser, Thr, and Val have half-lives of

ii. >10 hours in prokaryotes

iii. >20 hours in eukaryotes.

TLS Online TPP Program

#Question id: 860

#Unit 1. Molecules and their Interaction Relevant to Biology

Select true ‘T’ AND false ‘F’ about ubiquitinylation

I. These ubiquitin-like modifiers control processes as diverse as nuclear import,

II. Regulated by the ubiquitin-like modifier Sumo, and autophagy,

III. Regulated by the ubiquitin-like modifier Atg8.

IV. For a protein to be efficiently degraded, it must be linked to a chain of at least four tandemly linked ubiquitin molecules in which Lys 34 of each ubiquitin forms an isopeptide bond with the C-terminal carboxyl group of the following ubiquitin.