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TLS Online TPP Program

#Question id: 10461

Model of cry1 interactions with COP1/SPA1 in the regulation of photomorphogenesis, what will happen in the dark as well as in the light in wild type condition of cryptochrome?

a) In the dark, COP1/SPA1 acts to degrade transcription factors such as HY5, which is required for photomorphogenesis

b) In the dark, cry1 is activated by phosphorylation and forms a complex with COP1 and SPA1 via the C-terminal domain, preventing them from degrading protein HY5

c) In the light, COP1/SPA1 acts to degrade transcription factors such as HY5, which is required for photomorphogenesis

d) In the light, cry1 is activated directly by blue light and indirectly by blue light induced phosphorylation and forms a complex with COP1 and SPA1 via the C-terminal domain, preventing them from degrading protein HY5

e) In light as well as in dark both case cryptochrome perfom same function such as forming a complex with COP1/ SPA1 thereby promoting an increase in HY5 protein levels and transcription

Which of the following combinations from the above statements of cryptochrome is incorrect?

#Unit 6. System Physiology – Plant
  1. B, C and E     
  2. A, D and E
  3. A and D      
  4. C and E
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TLS Online TPP Program

#Question id: 12386

#Unit 7. System Physiology – Animal

Which of the following changes would you expect to find in a patient who developed acute renal failure after ingesting poisonous mushrooms that caused renal tubular necrosis?
TLS Online TPP Program

#Question id: 12385

#Unit 7. System Physiology – Animal

To evaluate kidney function in a 45-year-old woman with type II diabetes, you ask her to collect her urine over 24 hours. She collects 3600 ml of urine in that period. The clinical laboratory returns the following results after analyzing the patient’s urine and plasma samples: plasma creatinine = 4 mg/dL, urine creatinine = 32 mg/dL, plasma potassium = 5 mmol/L, and urine potassium = 10 mmol/L.
What is the net renal tubular reabsorption rate of potassium in this patient?
TLS Online TPP Program

#Question id: 12384

#Unit 7. System Physiology – Animal

To evaluate kidney function in a 45-year-old woman with type II diabetes, you ask her to collect her urine over 24 hours. She collects 3600 ml of urine in that period. The clinical laboratory returns the following results after analyzing the patient’s urine and plasma samples: plasma creatinine = 4 mg/dL, urine creatinine = 32 mg/dL, plasma potassium = 5 mmol/L, and urine potassium = 10 mmol/L.
What is this patient’s approximate GFR, assuming that she collected all her urine in the 24-hour period?
TLS Online TPP Program

#Question id: 12383

#Unit 7. System Physiology – Animal

Which of the following changes tends to increase urinary Ca++ excretion?
TLS Online TPP Program

#Question id: 12382

#Unit 7. System Physiology – Animal

A person with normal body fluid volumes weighs 60 kg and has an extracellular fluid volume of approximately 12.8 L, a blood volume of 4.3 L, and a hematocrit of 0.4; 57% of his body weight is water.
What is the approximate interstitial fluid volume?
TLS Online TPP Program

#Question id: 12381

#Unit 7. System Physiology – Animal

 A person with normal body fluid volumes weighs 60 kg and has an extracellular fluid volume of approximately 12.8 L, a blood volume of 4.3 L, and a hematocrit of 0.4; 57% of his body weight is water.
What is the approximate plasma volume?