#Question id: 10310
#Unit 6. System Physiology – Plant
Which of the following enzyme in the kreb’s cycle function as an allosteric enzyme found in matrix space?
#Question id: 1287
#Unit 4. Cell Communication and Cell Signaling
Biological roles of proteoglycans and hyaluronan include all of the following, except:
#Question id: 18079
#Unit 9. Diversity of Life Forms
#Question id: 1255
#Unit 4. Cell Communication and Cell Signaling
Following statements are regarding to the mechanism of action of cholera toxin.
A. cholera toxin is a homodimeric protein, target G proteins, interfering with normal signaling in host cells.
B. cholera toxin associates with a small G protein, known as ARF6.
C. association with ARF6 activates cholera toxin, which catalyzes the transfer of ADP-ribose from NAD+ to the critical Arg residue in the P loop of the alpha subunit of Gs.
D. ADP-ribosylation blocks the GEF activity of Gs and thereby renders Gs permanently inactive.
E. This results in continuous activation of the adenylyl cyclase of intestinal epithelial cells, chronically high cAMP, and active PKA dephosphorylates the CFTR Cl- channel and a sodium-proton exchanger in the intestinal epithelial cells.
Which of the following combination is correct?
#Question id: 1399
#Unit 4. Cell Communication and Cell Signaling
Loss-of-function mutations in which of the following genes typifies colorectal carcinomas?
a. myc b. K-ras c. p53 d. APC