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TLS Online TPP Program
#Question id: 12834
#Unit 2. Cellular Organization
How Aurora B and the spindle assembly checkpoint pathway collaborate during every cell cycle to accurately attach every single pair of sister chromatids to the mitotic spindle in the correct, bioriented manner?
TLS Online TPP Program
#Question id: 12486
#Unit 2. Cellular Organization
Which of the following process occur in prometaphase?
TLS Online TPP Program
#Question id: 12485
#Unit 2. Cellular Organization
Following statements are regarding to the centrosome cycle of an animal cell.
A. During G1, the daughter procentrioles continue to elongate.
B. During S phase, daughter procentrioles form adjacent to maternal centrioles so that two pairs of centrioles become visible within the centrosome.
C. During G2 phase, the centrosome contains a single pair of centrioles.
D. At the beginning of mitosis, the centrosome splits, with each pair of centrioles becoming part of its own centrosome. As they separate, the centrosomes organize the microtubule fibres that make up the mitotic spindle.
Which of the following option is correct?
TLS Online TPP Program
#Question id: 12484
#Unit 2. Cellular Organization
Match the following.
|
Column I |
Column II |
|
A. APC/CCdc20 |
i . responsible
for ubiquitinating proteins, such as mitotic cyclins |
|
B. APC/CCdh1 |
ii. responsible
for destroying proteins, such as securin |
|
|
iii. promotes
the metaphase–anaphase transition |
|
|
iv. Promotes
exit from mitosis |
Which of the following is correct?
TLS Online TPP Program
#Question id: 12483
#Unit 2. Cellular Organization
ATM and ATR are protein kinases that become activated following specific types of DNA damage.
A. ATM becomes activated in response to double‐strand breaks, which are detected by the MRN protein complex.
B. ATR becomes activated by protein‐coated ssDNA that forms when replication forks become stalled or the DNA is being repaired after various types of damage.
C. ATR phosphorylates and activates the checkpoint kinase Chk2, which phosphorylates p53. D. ATM phosphorylates and activates the checkpoint kinase Chk1, which phosphorylates and inactivates the phosphatase Cdc25.
Which of the following combination is incorrect?
TLS Online TPP Program
#Question id: 12482
#Unit 2. Cellular Organization
The Rb protein has been called the “master brake” of the cell cycle. How the Rb protein acts as a cell cycle brake?