TLS Online TPP Program

#Question id: 12387


An elderly patient complains of muscle weakness and lethargy. A urine specimen reveals a Na+ concentration of 600 mmol/L and an osmolarity of 1200 mOsm/L. Additional laboratory tests provide the following information: plasma Na+ concentration = 167 mmol/L, plasma renin activity = 4 ng angiotensin I/ml/hr (normal = 1), plasma antidiuretic hormone (ADH) = 60 pg/ml (normal = 3 pg/ml), and plasma aldosterone = 15 ng/dL (normal = 6 ng/dL). Which of the following is the most likely reason for this patient’s hypernatremia?

#Unit 7. System Physiology – Animal
  1. Dehydration caused by decreased fluid intake
  2. Syndrome of inappropriate ADH
  3. Nephrogenic diabetes insipidus
  4. Primary aldosteronism