Four different mutant lines showing similar phenotype were identified from a genetic screen. When genetic crosses among these mutants were carried out, the first mutant was found to complement the second, third and fourth mutant lines. However, no other complementation groups do the four mutant lines belongs to?

TLS Online TPP Program

#Question id: 24222

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following reaction of glycolysis is irreversible

1. Glucose is converted to glucose 6-phosphate in the presence of the enzyme hexokinase.

2. Fructose 6-phosphate is converted to fructose 1,6-biphosphate in the presence of the enzyme phosphofructokinase.

3. Phosphoenolpyruvate is converted to pyruvate in the presence of the enzyme pyruvate kinase.

4. isomerization of glucose 6-phosphate to fructose 6-phosphate

TLS Online TPP Program

#Question id: 24221

#Unit 1. Molecules and their Interaction Relevant to Biology

Glucagon lowers the cellular level of fructose 2,6 bisphosphate by

TLS Online TPP Program

#Question id: 24220

#Unit 1. Molecules and their Interaction Relevant to Biology

Glucagon stimulates cAMP from ATP. Cyclic AMP then activates cAMP-dependent protein kinase, phosphorylates PFK-2/FBPase-2. Phosphorylation of this protein enhances its FBPase-2 activity and inhibits its PFK-2 activity resulting

TLS Online TPP Program

#Question id: 24219

#Unit 1. Molecules and their Interaction Relevant to Biology

When Fructose 2,6-bisphosphate binds to its allosteric site on PFK-1 results

TLS Online TPP Program

#Question id: 24218

#Unit 1. Molecules and their Interaction Relevant to Biology

Phosphorylation of fructose 6-phosphate, catalysed by

TLS Online TPP Program

#Question id: 24217

#Unit 1. Molecules and their Interaction Relevant to Biology

Choose the correct statement of the following

a. In general, high acetyl-CoA or citrate are present, or when a high proportion of the cell’s adenylate is in the form of ATP, gluconeogenesis is favored.

b. When the level of AMP increases, it promotes glycolysis by stimulating PFK-1 by inhibiting FBPase-1

c. Phosphorylation of fructose 6-phosphate, catalysed by phosphofructokinase-2 (PFK-2)

d. Glucagon increases the cellular level of fructose 2,6 bisphosphate, stimulating glycolysis and inhibiting gluconeogenesis.