What is the difference between a linkage map and a physical map?

a) Genetic maps are based on recombination frequencies, but physical maps are based on restriction digestion.

b) Physical DNA map describes the absolute position of genes on a chromosome while genetic map so variable

c) Genetic maps are important to identify the origin of diseases, whether they are inherited or arise due to a random mutation.

#Question id: 902

#Unit 1. Molecules and their Interaction Relevant to Biology

Which demonstrates that the primary structure of a protein determines its tertiary structure?

#Question id: 1394

#Unit 4. Cell Communication and Cell Signaling

Apoptosis involves all but which of the following?

#Question id: 15265

#Unit 2. Cellular Organization

#Question id: 723

#Unit 1. Molecules and their Interaction Relevant to Biology

Common structural elements in proteins such as α-helices or β-sheets are characterized by uniformly repeating, energetically favorable main chain conformations which additionally exhibit a completely saturated hydrogen-bonding network of the main chain NH and CO groups. Although polyproline or polyglycine type II helices (PPII or PGII ) are frequently found in proteins, they are not considered as equivalent secondary structure elements. Which of the following statements are correct about PP and PGs.

A. PGII -like helices form hexagonal bundles which appear to fulfill the criterion of a (largely) saturated hydrogen-bonding network of the main-chain groups

B. main chain NH and CO groups of the central PGII -helix are saturated by either intra- or intermolecular hydrogen-bonds, resulting in a self-contained hydrogen-bonding network

C. The formation of the right-handed PPI helix is possible only with proline residues because of the required cis conformation. 

D. PPII helices seem to be stabilized by main chain-water hydrogen bonds (in the absence of main chain- main chain H-bonds), and tend to have a regular pattern of hydrogen bonds with water. After this, it is not surprising, that PPII helices are found mostly on the protein surface.

#Question id: 18225

#Unit 7. System Physiology – Animal