TLS Online TPP Program

#Question id: 15003


Laurie met her husband Jim at a support group for families dealing with PKU (phenylketonurea), a recessive genetic disorder. Laurie and Jim both have one sister who is affected with PKU and no other family history of the disorder. They come to you as a genetic counselor to ask what their risk is of having an affected child. What do you tell them?

#Unit 8. Inheritance Biology
  1. They must both be heterozygotes so their risk of having an affected child is ΒΌ.
  2. They must both be heterozygotes so their should tested to see if they carry the disease allele or not
  3. Since neither one of them is affected, they are not at risk of having an affected child.
  4. You can't give them any firm answers because you don't know their genotypes.
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TLS Online TPP Program

#Question id: 16956

#Unit 4. Cell Communication and Cell Signaling

Polyclonal antibodies are raised against bovine serum albumin in rabbit. Subsequently IgG in the antiserum is purified and digested with either pepsin or papain. Out of the following possibilities, which one is correct?

TLS Online TPP Program

#Question id: 16955

#Unit 4. Cell Communication and Cell Signaling

Stage thymocytes express neither CD4 nor CD8, markers associated with mature T cells. They are therefore called double negative (DN) cells. DN cells first travel to the region under the thymic capsule, a region referred to as the ________, where they proliferate and begin to generate their T-cell receptors. Thymocytes that successfully express TCRs begin to express both CD4 and CD8, becoming double positive (DP) cells, and populate the cortex, the site where most (85% or more) immature T cells are found.

TLS Online TPP Program

#Question id: 16954

#Unit 4. Cell Communication and Cell Signaling

match the following

 

 

A. endosteal niche

1. versatile cells that both generate bone and control the differentiation of HSCs

B. osteoblasts

2. line the blood vessels and also regulate HSC differentiation

C. reticular cells

3. send processes connecting cells to bone and blood vessels, and, unexpectedly

D. sympathetic neurons

4. can control the release of hematopoietic cells from the bone marrow.

TLS Online TPP Program

#Question id: 16953

#Unit 4. Cell Communication and Cell Signaling

The ability of any stem cell to self-renew and differentiate depends on the structural organization and cellular function of specialized anatomic microenvironments known as stem cell niches. These sequestered regions are typically populated by a supportive network of stromal cells. Stem cell niche stromal cells express soluble and membrane-bound proteins that regulate cell survival, proliferation, differentiation, and trafficking. Which statements is true about HSCs?

TLS Online TPP Program

#Question id: 16148

#Unit 4. Cell Communication and Cell Signaling

 Which statement is not true for NKT Cells?

TLS Online TPP Program

#Question id: 16147

#Unit 4. Cell Communication and Cell Signaling

 Which statement is not true for Natural killer (NK) cells?