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TLS Online TPP Program

#Question id: 9159

Which of the following investigations would shed the most light on the future distribution of organisms in temperate regions that are faced with climate change?

#Unit 9. Diversity of Life Forms

  1. Remove, to the mineral soil, all of the organisms from an experimental plot, and monitor the colonization of the area over time in terms of both species diversity and abundance.

  2. Look at the climatic changes that occurred since the last ice age and how species redistributed as glaciers melted, then make predictions on future distribution in species based on past trends.

  3. Compare and contrast the flora and fauna of warm/cold/dry/wet climates to shed light on how they evolved to be suited to their present-day environment.

  4. Quantify the impact of man's activities on present-day populations of threatened and endangered species to assess the rate of extirpation and extinction.
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TLS Online TPP Program

#Question id: 1519

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to the FOXO3a protein.

A. In the presence of growth factors, FOXO3a is non phosphorylated and mainly localizes to the nucleus, where it activates transcription of several genes encoding pro-apoptotic proteins.

B. When growth factors are removed from the cells, PKB becomes active and phosphorylates FOXO3a.

C. Phosphorylated FOXO3a binds to cytosolic phosphoserine-binding protein 14-3-3 to bind FOXO3a and thus sequester it in the cytosol.

D. Dephosphorylated FOXO3a binds to cytosolic phosphoserine-binding protein 14-3-3 to bind FOXO3a and thus sequester it in the cytosol.

Which of the following is correct?
TLS Online TPP Program

#Question id: 1518

#Unit 4. Cell Communication and Cell Signaling

Following statements are regarding to the some cancers harbor characteristic chromosome alterations. Chronic myelogenous leukemia (CML), a common leukemia in humans, was found to be associated with the Philadelphia chromosome.

A. Philadelphia chromosome is generated by a translocation between chromosomes 22 and 9. The two chromosomes exchange their terminal regions, which leads to a characteristic alteration in the size of chromosome 9.

B. At the breakpoint of this translocation, a new fusion protein, the BCR-ABL fusion, is generated.

C. The BCR-ABL fusion protein is a constitutively active kinase that phosphorylates multiple signal-transducing proteins.

D. If this translocation occurs in a hematopoietic cell in the bone marrow, the activity of the chimeric BCR-ABL oncogene dephosphorylate proteins thereby activating many intracellular signal-transducing proteins.

Which of the following statements are incorrect?
TLS Online TPP Program

#Question id: 1263

#Unit 4. Cell Communication and Cell Signaling

The major classes of CAMs include

a. cadherins.    b. fibronectin.    c. Ig-superfamily CAMs.      d. P-selectins.
TLS Online TPP Program

#Question id: 1264

#Unit 4. Cell Communication and Cell Signaling

 Desmosomes
TLS Online TPP Program

#Question id: 1265

#Unit 4. Cell Communication and Cell Signaling

An example of an integrin containing cell junction is
TLS Online TPP Program

#Question id: 1266

#Unit 4. Cell Communication and Cell Signaling

Integrins